ID   W3XJY2_PESFW            Unreviewed;      1417 AA.
AC   W3XJY2;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PFICI_03787 {ECO:0000313|EMBL:ETS85762.1};
OS   Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX   NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS85762.1, ECO:0000313|Proteomes:UP000030651};
RN   [1] {ECO:0000313|Proteomes:UP000030651}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX   PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA   Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA   Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT   "Genomic and transcriptomic analysis of the endophytic fungus
RT   Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT   of natural products.";
RL   BMC Genomics 16:28-28(2015).
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DR   EMBL; KI912110; ETS85762.1; -; Genomic_DNA.
DR   RefSeq; XP_007830559.1; XM_007832368.1.
DR   STRING; 1229662.W3XJY2; -.
DR   GeneID; 19268800; -.
DR   KEGG; pfy:PFICI_03787; -.
DR   eggNOG; ENOG502QU87; Eukaryota.
DR   HOGENOM; CLU_001720_0_0_1; -.
DR   InParanoid; W3XJY2; -.
DR   OMA; TKVEWLW; -.
DR   OrthoDB; 2027807at2759; -.
DR   Proteomes; UP000030651; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd07609; BAR_SIP3_fungi; 1.
DR   CDD; cd13280; PH_SIP3; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR039463; Sip3/Lam1_BAR.
DR   InterPro; IPR042067; Sip3_PH.
DR   InterPro; IPR031968; VASt.
DR   PANTHER; PTHR14248; CYCLIN Y, ISOFORM A; 1.
DR   PANTHER; PTHR14248:SF18; CYCLIN Y, ISOFORM A; 1.
DR   Pfam; PF16746; BAR_3; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF16016; VASt; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS51778; VAST; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030651};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        1156..1175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1187..1211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          316..415
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          936..1106
FT                   /note="VASt"
FT                   /evidence="ECO:0000259|PROSITE:PS51778"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          472..510
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          530..607
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        567..587
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1417 AA;  157785 MW;  92785EBFC6CC4D6F CRC64;
     MSDPTTAERA PPTPSAPNIP TQASRHGNPL ISVLLNEAGL DSPTFRSNAL HFAEQVDAIE
     RWLEGYSRTA ARLSHDMLGL EAVVNDYLAK VIPPQNVVSL DHDYTALALK RISEGSREWW
     THILGLAKKM DTMSAEPIRN FLQNDLRTFK ETRRNLDQTQ KTFDSTLARY LGLSKAKEPS
     AIREEAFSVY ETRKAYLKAS MDFCQMAPQL RFTLDKLLVR VSTDIWREMK RSKDTAGSFG
     KWGQQMDRVR GWSKEMELTE STFKRELQAA RREVGESSVV AFKPSRELDA YSASTVPFLG
     SKGPLSVNTD EKAGVYSEKQ GWLYLRTMTG KPVRTTWIRR WYYCRDGIFG WLVSGPQGVL
     TGDEIGVLLC NAKPAISEER RFCFEVKTKN QTLMLQAETQ SELMGWLEVF EVAKKKAFEA
     SVGRDTSSLP GGVDPAFAIT PPSMPEFSAK TMDAQLGLEE PGPAFEKTNT LPIPGQENSG
     IPRASFDVIS SGPRRSATAL GREEGESGRD HAARIMQKLD LHRKANFSST TDVSAGMPSP
     GPSGGIASLI SASHGLLPGY PSPIIGQMAS RPQQQQQQQT PTLSGPEPQA GSLAPATLAS
     PPAPTSLSKT AVVYSSDRTL TNDTGPGLPT AIMANYWGSN AWAQEYAPKP VKTEFNPDDP
     FGPNSPSIKM TMTNELGELK ASTPTHKKAI SMDAKILHPA NIKEKSTQEQ FPPGYPLELK
     TNTAQFRLVF PNVPLDEKLV LVFRASWTTS TSERSRDSPG MAGNGRIYVT PDNMYFYGHQ
     MGLVVAYAIP LDTITEVTAA PGRDCDFIFL HLNQDAPDVQ YSRISIKTFL EDMDLLHARL
     NLLVDDLQAE EPMEVMDLIK ALINFENEEY DRRSPSAGSW EEVSANTPVD NNTLAGRAVS
     PRADLYAKSR ARGAMRKPAP KLQLPAHPVH YEPEDMQRKV AERTFEISAK ACFHVLFGDK
     SFVFPKLYFE RRAKQIAQGP WTVGDAGRLQ RLFNFKVKYG TMFGQAREED ITDQQTVEVF
     SDHVTYVVTH VKTPWHLPHA GAFKLVTKIV ITHIAKSKCK LAIFTKVAWS KAVLSKNIVE
     RQALDDADMD AEELAEVATD QVRKIGPHSR TKRAIQIYGN IGQQTQVVLF SPADTEKTRK
     THIRPHSLTS MLFDTVRSFA ESALTSIIMF AFAGLKKLWD VVTAQRILLA VLAFSFIVNI
     VFSSQGASTW WSERKAAGFM QRLGVGPNVM MSKAIYLRDL DEAARFSSLD NSWPAEDSSC
     YATFQSIANS TDIDAPYEGA GATLSSASSR ATARRLRRSR QRLGTYRHDL LVAMRMVNSV
     EREMIQGEWE NWLIDENYRC EQVAGVLRLW NTTASDDKTA GKGGSVVAVD SELQQKILQE
     KDERKKETLM SWYTDYCGSC KQDKDDLMRD RERLSLA
//