ID W3Y7E6_9FIRM Unreviewed; 514 AA.
AC W3Y7E6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335,
GN ECO:0000313|EMBL:ETS93436.1};
GN ORFNames=HMPREF1521_0580 {ECO:0000313|EMBL:ETS93436.1};
OS Veillonella sp. AS16.
OC Bacteria; Bacillota; Negativicutes; Veillonellales; Veillonellaceae;
OC Veillonella.
OX NCBI_TaxID=936589 {ECO:0000313|EMBL:ETS93436.1, ECO:0000313|Proteomes:UP000019042};
RN [1] {ECO:0000313|EMBL:ETS93436.1, ECO:0000313|Proteomes:UP000019042}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AS16 {ECO:0000313|EMBL:ETS93436.1,
RC ECO:0000313|Proteomes:UP000019042};
RA Durkin A.S., McCorrison J., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETS93436.1}.
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DR EMBL; AZYX01000007; ETS93436.1; -; Genomic_DNA.
DR AlphaFoldDB; W3Y7E6; -.
DR PATRIC; fig|936589.3.peg.588; -.
DR eggNOG; COG1418; Bacteria.
DR Proteomes; UP000019042; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 3.30.300.20; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}; Transmembrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00335}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00335"
FT DOMAIN 330..423
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT COILED 27..133
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 514 AA; 57714 MW; 50CCA44CF7249D44 CRC64;
MSLILEYSLI AVVMVLIGLG VGYFLRKNIA EGKLNQAEQE AERIIANGVR TAESKKKEAL
LEAKEEIHKL RSDVERENKD RRSELQRMER RILQKEESLD KKLDNIEHKE EALHRKEADL
AHSREKVEAL YEKQMAELER ISGMTFEEAK NILLTNVEQE IRHETAIMVK EMEQQAKDEA
EKKAKEIISS AIQRCAADHV AETTVSVVAL PNDEMKGRII GREGRNIRAL ETLTGIDLII
DDTPEAVILS GFDPIRREVA RIALEKLIVD GRIHPARIEE MVGKARKEVD QTIKEAGEQA
TFEADVHGLH PEIVKILGRL KYRTSYGQNV LKHSIEVSHL AGLMAAELGC DVTLAKRGGL
IHDIGKALDR ELEGSHVQIG VDVARKYRES AAVINCIGAH HGDEEFQTVE AVLVAAADAI
SAARPGARRE TLENYLKRLS KLEEIAESFE GVEKCFAIQA GREIRVVVKP DKIDEADSTL
LVRNIVKRIE SELEYPGQIK VVVIRETRVV DYAK
//
