ID W4AJN6_9BACL Unreviewed; 501 AA.
AC W4AJN6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:ETT31086.1};
GN ORFNames=C169_25980 {ECO:0000313|EMBL:ETT31086.1};
OS Paenibacillus sp. FSL R5-808.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1227076 {ECO:0000313|EMBL:ETT31086.1, ECO:0000313|Proteomes:UP000019053};
RN [1] {ECO:0000313|EMBL:ETT31086.1, ECO:0000313|Proteomes:UP000019053}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL R5-808 {ECO:0000313|EMBL:ETT31086.1,
RC ECO:0000313|Proteomes:UP000019053};
RX PubMed=24422886; DOI=10.1186/1471-2164-15-26;
RA Moreno Switt A.I., Andrus A.D., Ranieri M.L., Orsi R.H., Ivy R.,
RA den Bakker H.C., Martin N.H., Wiedmann M., Boor K.J.;
RT "Genomic comparison of sporeforming bacilli isolated from milk.";
RL BMC Genomics 15:26-26(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETT31086.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ASPT01000068; ETT31086.1; -; Genomic_DNA.
DR RefSeq; WP_006208042.1; NZ_ASPT01000068.1.
DR AlphaFoldDB; W4AJN6; -.
DR PATRIC; fig|1227076.4.peg.5336; -.
DR Proteomes; UP000019053; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR037522; HD_GYP_dom.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000313|EMBL:ETT31086.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 252..303
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 305..501
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT DOMAIN 327..452
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 501 AA; 56398 MW; 1A3FF0AF4DC561C8 CRC64;
MQLYKSFLKQ LIRNYMIGSS AAVLVVGGVL MVTTLDIPFE EGARLMIILA ISFMVMIASE
LTIFLRHLRP IHAGFDEDNI DLEVLEKAYL SVHRMPRMAV YRIFGPHLLG LSLPAIVLTV
WMMEQGKLNF PPFYIWLACL GAILLASCHA MIEFFLTIAA IRPLIKEIRR QALSRYGVDF
SLEGHVFMAI RTKFLLSTML IGTFPLFLFS LAVQIRLEGL SQIIAQQYWG WAGFILLLGV
GFAYVGAWLL TQDLQRPIRQ LYRAMNEIKE GRLIQTSNLY SDEFSNLIAG FNMMVRGLQV
REERNRKLLD SYFAALAAAL DARDPYTAGH SLRVAEYSVL IGRLAGLSEK EVDILHKTAL
LHDIGKIGVR DNILLKEGKL TAEEFDQVKA HPAQGENILL QIEPADAMAP YLEGVRSHHE
RYDGAGYPDG LKGKEIPLFG RIIAVADAYD AMTSDRPYRS GMKSVDALNI LEAGRGTQWD
PDYAGMFVKY MKTEKKVISI R
//
