ID W4AWH3_9BACL Unreviewed; 810 AA.
AC W4AWH3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=PAS/PAC sensor signal transduction histidine kinase {ECO:0000313|EMBL:ETT35870.1};
GN ORFNames=C169_15879 {ECO:0000313|EMBL:ETT35870.1};
OS Paenibacillus sp. FSL R5-808.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1227076 {ECO:0000313|EMBL:ETT35870.1, ECO:0000313|Proteomes:UP000019053};
RN [1] {ECO:0000313|EMBL:ETT35870.1, ECO:0000313|Proteomes:UP000019053}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL R5-808 {ECO:0000313|EMBL:ETT35870.1,
RC ECO:0000313|Proteomes:UP000019053};
RX PubMed=24422886; DOI=10.1186/1471-2164-15-26;
RA Moreno Switt A.I., Andrus A.D., Ranieri M.L., Orsi R.H., Ivy R.,
RA den Bakker H.C., Martin N.H., Wiedmann M., Boor K.J.;
RT "Genomic comparison of sporeforming bacilli isolated from milk.";
RL BMC Genomics 15:26-26(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETT35870.1}.
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DR EMBL; ASPT01000027; ETT35870.1; -; Genomic_DNA.
DR RefSeq; WP_036641216.1; NZ_ASPT01000027.1.
DR AlphaFoldDB; W4AWH3; -.
DR PATRIC; fig|1227076.4.peg.3278; -.
DR Proteomes; UP000019053; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF65; SENSOR HISTIDINE KINASE COMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ETT35870.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..116
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 118..170
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 721..810
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 810 AA; 92947 MW; 5CD64680C268A920 CRC64;
MCNYFLGTAT LILVILTTTF TMFLYRYRYP RRLSRQSLDL AEGRFHMLDE MLLTLDVGIW
SYDIGTRSIM NTSLAFQKIT GYSRSDFSDG LTWETMIHPE DMPLFQSLVH KLRHGEAVHT
EYRIIHAEGD IRWVQVKMIP TMNESRQTAR VDGIAIDITS RFRMEEALYD ITECKKMEIA
LKESMNRYRR LVEMSPIAIA VCKERKLMYV NPAGLRILGA AGPEDILGTD PWDWVLNSYE
EWARKRHAEL IRKGHVFPEE LSLRRVDGAR VDVVTTALYD AESTTIEIFF EDITARKSAE
RALMESDRIN RHILDIAPVA MFLHSDFAYI YANPAGFDLL GITDVAQLDG TSFLDVIPTD
QIEFVISEVE HVYESGMTSQ LTENKLVRLD GTIIDIEAVT TRIPYIGHNT ALTIIRDITE
KKKAERERIA AERLVRESED RYFRLQMSLD RFSSDLFGMV KISELNARIV QEIQEVLETD
RVSLIQINHH SLHIKIQGGC KVLPPGVLTA IHNCGPEHIP LCTLFEMCDG YFVKIGEMNG
DTSMVCIGGE VPLLMIQAKK IWLETISRYA SVLYDNFRVI EDLTRELDKL GSSQQIMPLW
LLRLMLHLSE NERKRLSQDL HDAALQEQVI WYRKLNQIVS DHELPEGLRR QLEEIEEGLL
DVIYQIRITC NELRPPLLKE EGLERSLEAL FEFTQLRTNY SIQFDCSNFD DDISDDHLIG
LYRIVQELLA NATKHSNATE VKLTLSTQSD EVSLSYEDNG IGIDRTQKPN QFNNMGIGGM
KERVRSMNGK IQFESSDSGG LAVYIQITAK
//
