ID   W4B6A5_9BACL            Unreviewed;       464 AA.
AC   W4B6A5;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=L-cystine uptake protein TcyP {ECO:0000256|ARBA:ARBA00022031};
DE   AltName: Full=Transporter of cystine TcyP {ECO:0000256|ARBA:ARBA00031293};
GN   ORFNames=C169_10643 {ECO:0000313|EMBL:ETT39288.1};
OS   Paenibacillus sp. FSL R5-808.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1227076 {ECO:0000313|EMBL:ETT39288.1, ECO:0000313|Proteomes:UP000019053};
RN   [1] {ECO:0000313|EMBL:ETT39288.1, ECO:0000313|Proteomes:UP000019053}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FSL R5-808 {ECO:0000313|EMBL:ETT39288.1,
RC   ECO:0000313|Proteomes:UP000019053};
RX   PubMed=24422886; DOI=10.1186/1471-2164-15-26;
RA   Moreno Switt A.I., Andrus A.D., Ranieri M.L., Orsi R.H., Ivy R.,
RA   den Bakker H.C., Martin N.H., Wiedmann M., Boor K.J.;
RT   "Genomic comparison of sporeforming bacilli isolated from milk.";
RL   BMC Genomics 15:26-26(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETT39288.1}.
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DR   EMBL; ASPT01000018; ETT39288.1; -; Genomic_DNA.
DR   RefSeq; WP_006212297.1; NZ_ASPT01000018.1.
DR   AlphaFoldDB; W4B6A5; -.
DR   PATRIC; fig|1227076.4.peg.2206; -.
DR   Proteomes; UP000019053; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865:SF5; L-CYSTINE TRANSPORTER TCYP; 1.
DR   PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR   Pfam; PF00375; SDF; 1.
DR   PRINTS; PR00173; EDTRNSPORT.
DR   SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        6..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        34..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        72..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        395..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   464 AA;  49581 MW;  49F59810DE5389A2 CRC64;
     METLWVIINV LVLILLVGIL YWMQKKHYSF TKRVFAGLGL GVLFGVALQL IYTSTSDVVV
     KSTDWFNLIG YGYVRLLQMM VIPLIMVSII SAIMKLKGGR NVGKMSGLII TVLLLTTAVA
     AAVGITTALA FDLSAVNIQG GAAEEQQGAL LQERLGDVEG RTLPQQILDF IPSNPFADMT
     GARRTSTIAV VIFSAFIGIA VLGLDRKNKE QAETFRNMIS AVYGVVMRIV TLVLRLTPYG
     ILALMAKTIA TTDLQVIMNL IDFVLASYVA LIVMFIIHLV LLAIFGFNPL KYVKKVFPTL
     TFAFTSRSSA ATIPLNVQTQ NKKLGVSEGI ANLSASFGAT IGQNGCAGIY PAMLAVMIAP
     TAGVDPTSWS FILTLIVVVM ISSFGVAGVG GGATFASLIV LSTMNLPVAL AGLLISVEPL
     IDMGRTALNV NDSMTAGVIT GKVMNEVDKD VFNDDNIELD LVQG
//