ID W4CUG8_9BACL Unreviewed; 328 AA.
AC W4CUG8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=2-oxoisovalerate dehydrogenase subunit beta {ECO:0000313|EMBL:ETT59389.1};
GN ORFNames=C173_29476 {ECO:0000313|EMBL:ETT59389.1};
OS Paenibacillus sp. FSL R7-277.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1227352 {ECO:0000313|EMBL:ETT59389.1, ECO:0000313|Proteomes:UP000019051};
RN [1] {ECO:0000313|EMBL:ETT59389.1, ECO:0000313|Proteomes:UP000019051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL R7-277 {ECO:0000313|EMBL:ETT59389.1,
RC ECO:0000313|Proteomes:UP000019051};
RX PubMed=24422886; DOI=10.1186/1471-2164-15-26;
RA Moreno Switt A.I., Andrus A.D., Ranieri M.L., Orsi R.H., Ivy R.,
RA den Bakker H.C., Martin N.H., Wiedmann M., Boor K.J.;
RT "Genomic comparison of sporeforming bacilli isolated from milk.";
RL BMC Genomics 15:26-26(2014).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETT59389.1}.
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DR EMBL; ASPX01000115; ETT59389.1; -; Genomic_DNA.
DR RefSeq; WP_036698320.1; NZ_ASPX01000115.1.
DR AlphaFoldDB; W4CUG8; -.
DR PATRIC; fig|1227352.4.peg.5896; -.
DR eggNOG; COG0022; Bacteria.
DR OrthoDB; 9771835at2; -.
DR Proteomes; UP000019051; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
FT DOMAIN 4..179
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 328 AA; 35734 MW; EC8294258D88654F CRC64;
MAMMEYIDAI RLAMKEEMER DESVFVLGED VGVKGGVFTT TKGLQEQFGA ERVLDTPLAE
SAIAGVAIGA AMYGMKPIAE MQYSDFMLPA TNQIISEAAK IRYRSNNDWN CPVVIRAPIG
GGIFGGLYHS QCPESIFFGT PGLKIVAPYS AADAKGLLKA AVRDPDPVLF FENKKCYKLI
KGDVPEGDYT VPIGEANLLR EGSDITVIGY SLPLHFAMQA AEELEKEHGV TAHILDLRTL
QPLDREAIIA AVRQTGKVLI VHEDNKTGGI GAEVAAIIAE HCLFDLDAPI FRLCGPDVPA
MPISPPMEKF FLLSKDKVKA EMLRLAQY
//
