ID W4J228_PLAFP Unreviewed; 1950 AA.
AC W4J228;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 03-MAY-2023, entry version 34.
DE RecName: Full=G domain-containing protein {ECO:0000259|Pfam:PF01926};
GN ORFNames=PFUGPA_02430 {ECO:0000313|EMBL:ETW55667.1};
OS Plasmodium falciparum (isolate Palo Alto / Uganda).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57270 {ECO:0000313|EMBL:ETW55667.1, ECO:0000313|Proteomes:UP000019103};
RN [1] {ECO:0000313|EMBL:ETW55667.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW55667.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW55667.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW55667.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI927340; ETW55667.1; -; Genomic_DNA.
DR EnsemblProtists; ETW55667; ETW55667; PFUGPA_02430.
DR OMA; DNNGDYY; -.
DR Proteomes; UP000019103; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46434; GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL; 1.
DR PANTHER; PTHR46434:SF4; PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019103};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1712..1777
FT /note="G"
FT /evidence="ECO:0000259|Pfam:PF01926"
FT REGION 391..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1142..1185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1231..1287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1639..1659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 603..659
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 425..486
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..521
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..578
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1142..1165
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1166..1185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1273
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1950 AA; 233557 MW; 353CEB2CB1032758 CRC64;
MFMKFIYAWS IYILIYTKCN SYILRKKYLD NLFFVNYDTV PLYDYNRRCV IYDKANKRWK
LRNQRIYKKE QNDEREKGKV NRFTRCYLLN NNEFRQYDKK LKKRRKEKEG ILFSKFDKMF
KESFNEDDKL KKSELISILA CICTNIVIEF LKLKEEKKTE DFTYTFDYSV MNVLKMVNFE
YDVNEELKKQ KKKKKMNKTY TSLYGEIKGG GNKKIDDYND NIHMKKNEDP TINNSLFNEE
RIGANDKIEM FEETKEINID INNKNTKEEN ELLDMYIQKL EFNTLEMNEI KTYIDLFFGK
NTYEKVFVKN NININKIFDV LHTALFDKTQ ERENVMQLQQ FVDNQEKKLN EKKINVRNIN
TFNDYLDKYV SLEEEKNIND LDNILYDDEK YESEQERTSE KKCMRKKKKK GTKSLDRVNM
DIDNDGDNNN DDDDNNNDDD DNNNDDNNND DNNNNGDDDN SEDNDNSGDY YDNNGEDNDN
NGEDNDNNGD YYDNNGDYYD NNGDDNDNNG DDNDNNGDDN DNNGDNNDNN GDDNNNNYNN
IDKDNTNNSN SNKHRKHDNY YNELSNDQHN KDNHNPNNHN MNRKTQHNNS HEEENRYINK
IHVKNIEEDR NFSKNNNEDK KKNHEEEKKF LSGLSYALIK GCNIQMEHKE EKMNEEKNEC
CTTHYDDKKL ESCHDNQNHI ILLNFIYDNK YNIEFRTDVG VVAYDLLKNE FVEDNIEECL
IKDIKLNHVF NKDIINIFEN IIKNLNLNVI CSLPYKKRFY EKQKLIKDIN NKINFHNLND
EMLHMLLYIY FIIWGEDLHF YELKKVHIEP IKKEDINKSM NTNNYVDNKN ENILSAHNFF
VNFNYNDNDD IIIDSDTYNN NLSKNKNNLF DSTFFENDYI SLNLKIFINN KKEINNYDEL
KNAFNIYKCN LSEYIQNFLK SINEKDLNFV TPEYFVKNYI YNTNDEFINI TEILYKCKVQ
KKYISLYPEQ TNSMERNKKT HFKLYYSCPT SAPLVNTKIK MLQNKYGFIK NFKSNIFKIN
KKNNNNIIKY YHDCNYNKND YDCNKNDYDY NKNDYDYNYN NSETPVGRYS FFLFSKNKKK
YETVNKKEKS KYYQTINGNN NISTTCDFLS NEQFDEEIEN FEHIDNILGH HNYDNFNEEE
IENTNTKQDP SNKINHYEKS KMDKSNGPTD NNNLTCERTK SSNNNPYLQK MFEKQKYMNN
ILSLTNMNNN IKQNVHVLSY EDAYSNIKND LKNKSKDKKK KKRNQNDDND YNDDDNDDVN
NDDDNDDVNN DDDNNNDNNN NYYYHNNNMD EQNNILEQID EEKIEKQLTS LLQNKDNYDM
IKENEEKKKN KELEKLNNEK EKISTFFKNM NVEIKLNKNV CVGCGAIFQS KDMNKFGFLK
NDIYEKIINK DEDLDKKNIL SEIYEENKKT NTNISDINII YKNDTINELY KLKEMNIKKM
SEDDNKKIQY DEDHNVNNNN NIDNNFLKVQ NNINKNEMDE DIMDQKQYIC KRCFDLKHKN
KITNNLIINY TNNNEINVQD FEKYVINIFK KKCFIIYIVD VLDLYVYSNL KKLFNLYKKL
HNDKSKLEGF YFCVNKIDLL SNYKEFTVKN YIYNFLKSNK INVLFKNIFL VSAKTGYNVK
KLIYTVFMRS KNILRNTKKK NKQNLDEEEE EDTEEDEDMD SLQYDLNDYD LIKYRKELFS
NDNKNNFLNE QLDENNYNDN DLKNYYSKNV NIYIVGNANS GKSSLINYLL KNVKNKEKKN
FLISHSIIPG TTLKNIKIKL NKNITINDTP GIISNNSILS YLNFEELKYV VCNKLKNKIT
SIYINENDYI FIGGLLYIHI LNIKKYYSIM SFFLSEKLPI IKRKNFSKDP SMFIKQKIKT
GFLYPPFKEE RFDEINNFKK YYFNINNQAV DIKNSSYDIH IQGMGYITFY SFENIEFNLY
TLKNVDVMTR PSIMPYHKKF GKLNFTKKLK
//
