ID W4J4H8_PLAFP Unreviewed; 1203 AA.
AC W4J4H8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=TFIIS N-terminal domain-containing protein {ECO:0000259|PROSITE:PS51319};
GN ORFNames=PFUGPA_01130 {ECO:0000313|EMBL:ETW56929.1};
OS Plasmodium falciparum (isolate Palo Alto / Uganda).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57270 {ECO:0000313|EMBL:ETW56929.1, ECO:0000313|Proteomes:UP000019103};
RN [1] {ECO:0000313|EMBL:ETW56929.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW56929.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW56929.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW56929.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
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DR EMBL; KI927296; ETW56929.1; -; Genomic_DNA.
DR AlphaFoldDB; W4J4H8; -.
DR EnsemblProtists; ETW56929; ETW56929; PFUGPA_01130.
DR OMA; PCLFEDK; -.
DR Proteomes; UP000019103; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR Pfam; PF08711; Med26; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649};
KW Reference proteome {ECO:0000313|Proteomes:UP000019103}.
FT DOMAIN 352..437
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 53..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..814
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 925..966
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 166..200
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 462..489
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 64..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..793
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..814
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1203 AA; 140668 MW; DF49E776F3F42464 CRC64;
MENISIENIN VNEIHNKKRK QNVVQKKNIS NHEMINTSTD IVISGENHKP KELIKRTKKK
SKISNAGNME ISQENDEGKN SLSLEGYLKN GDNIDDVYNY NSSNNNEEDE KNVDIINNDY
KTKDDTNNIL ILNNNNNNNN NKLNSILPQD NSDDNKSINI CEDGNINNEN KKKKNNKEII
SELKNTLNIV ENSNAQHNIE GLNKEEITML DSWYFANKMK IIPYLFDDKP IHINLLNSLY
MLHPYFKNHK TKIIIYLRFV KNKYQNIIKK NSEKYNNQTI EIECKATMLK ILGNKIENFK
DIQYMDKVIT LIQNENSYIN IKYFFLFILD VSNDYIIYEN FLQQNGLLCI KNILHNIAEK
KIIKKNIPLL IILLNFLKNL NINLNHLKTT LIGIPINFIA RNKIDEQNNL DYVTDNSKVI
QLAKELINKW KLIRDQALNN NNNNNNNENQ NDQNGQIEIV NINKVEKDIE EAQKENANNN
NNNNNFMSNM INATTNHHIN IINDTKPKSN KKSANSVSKN ENKNIMLEII DNINEEYEKK
KKRHLEYKKA KIEGKIKKFS ALKNSTEIKK KTENLLINLS KDNLIRPHSD NNNNNNNNNR
IHSNPMINNN ILSHNMNGMD YNGIYSNDRK NYNNNNNIIN NEHLSRDIYN DGMASSYNHM
NKNVHSQNYT RMGDHSMDSP NYMNKYNMNN RHNSNEASTN RQPFPQYGPI NTPPSINKKN
AHSNNNNNNN NKYINDNYYN NNSMIPNKYS PDGRYSPSNL HTKQFQNEKY GNVSPHINDP
LINKNNYERH NYNPSNRHTY DRKSNEKNYK PSKFSTKRTN KFTYDESPFD NNINVKDAKQ
NIKDPFEYYS NNNMQKEPYK NNKKLEIENI RNLLNIDANV SSQQYDNNDI NEQMNIQTMK
NDNNFKNSKQ KRIMEQFESL NLLLNGSNIN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
NMDEPLDSSL DDIFSFFKKF ENVQENYQIN KSDFIYPASI FQDSEIKKND IIITFKYDSH
DNIPIYIKYN TPSNKNMINT KFSNNNYPNQ LNNTEPYNNM DRDHIIKNSN QNFNILPLSE
LFHQSNINEL KLPPIMPPIL PNLNNSQNII PPIMFPYNNS NDYTNTNINS AFSSDNISYN
NNSSINEFVK IFDEGIQKIL LKNKDLANLL MNKPDVVQKM LKGPQYINEA LSSLENELKN
WNR
//
