ID W4J503_PLAFP Unreviewed; 868 AA.
AC W4J503;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=PFUGPA_01501 {ECO:0000313|EMBL:ETW56711.1};
OS Plasmodium falciparum (isolate Palo Alto / Uganda).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57270 {ECO:0000313|EMBL:ETW56711.1, ECO:0000313|Proteomes:UP000019103};
RN [1] {ECO:0000313|EMBL:ETW56711.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW56711.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW56711.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW56711.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI927303; ETW56711.1; -; Genomic_DNA.
DR AlphaFoldDB; W4J503; -.
DR EnsemblProtists; ETW56711; ETW56711; PFUGPA_01501.
DR OMA; YDNFRCP; -.
DR Proteomes; UP000019103; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR PANTHER; PTHR23327:SF50; TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019103};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 79..117
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 558..608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..598
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 868 AA; 105673 MW; 7E0B889AC11DD410 CRC64;
MAGYFFGNVQ NNLNRARHSL TNTLSDMRLD ESYLKSIRMN IKKRFDKLMN KIIPFETIDE
NKRFVVIIEK KKNYENFRCP ICMLILFKPV KTKCGHIFCR ECIEKVLLKF DYCPLCRNFI
KDKKLENVEN STLGSEYENI KIRCYKCKEI TNIKNYEKHI INHIMNIHKS FDNIKNYSTS
EEGDNYNFLS IQKKKKNSNY IYSISNNNYI HNIYHHINPY NFDSYFNKKF QIIYMKEFFN
LLKEHNINTH IDNFYLLYAQ NVLYDFKHIN VEVQDIMCDV FLIIKIRKKR KNYHQNNLNL
LYLDNSKYKS EQINNIITSK DDINMNVNMN IHTNIHTNIH TNIHTNIHTN IHANDGFISS
EGEKKKDIKQ NNFITNDLKK QKSIIFSSYK KKLYTNDTFE MYQKKLLIHN KKTPNKYIYI
LFEYNTKNIF FTLLQNIPVF KNMNIIKLVK YKNKKMNSIG HTTNISEQLI RLFSILNEKR
ILRTYHKYFY NSIHLFHELI YSLLFSKHQK EKNENIENID VAYMQDIYEM ERSYQMEEKQ
LNDVNYHIYQ KCDHYENNQN EQNDQNEEPY QHYNDQNEEP YQHYNDQNEK PYQHYNDQNE
QPSEHHNDNY YNFVEKNEHN FKNIFLKDYE LMFILFYLKY EYRLPLKCEY LYLYSENFIA
KILRDQEREQ DIFISNVYSY HNLDILQNKI NGENILPLSN NEFVKNDKGI IIILQVQRGK
LKNEYKSDIN IIDNKNNCND ILNNNQYINQ TEENINNSEY TNKKDFYKKY VQKKSNKTNT
HTKNINQYYD IHNVCYLIIS YSSKGFQWYL NNSLNFLNKK QIEYKSQEVF FLIDKLILFF
FNIRNKKYSS VFWNSTHLFQ CMLNFCCE
//
