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Database: UniProt
Entry: W4K1F9_9HOMO
LinkDB: W4K1F9_9HOMO
Original site: W4K1F9_9HOMO 
ID   W4K1F9_9HOMO            Unreviewed;      1123 AA.
AC   W4K1F9;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   16-JAN-2019, entry version 28.
DE   RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE            EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN   ORFNames=HETIRDRAFT_452773 {ECO:0000313|EMBL:ETW79663.1};
OS   Heterobasidion irregulare TC 32-1.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Agaricomycetes; Russulales; Bondarzewiaceae; Heterobasidion;
OC   Heterobasidion annosum species complex.
OX   NCBI_TaxID=747525 {ECO:0000313|EMBL:ETW79663.1, ECO:0000313|Proteomes:UP000030671};
RN   [1] {ECO:0000313|EMBL:ETW79663.1, ECO:0000313|Proteomes:UP000030671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TC 32-1 {ECO:0000313|EMBL:ETW79663.1,
RC   ECO:0000313|Proteomes:UP000030671};
RX   PubMed=22463738; DOI=10.1111/j.1469-8137.2012.04128.x;
RA   Olson A., Aerts A., Asiegbu F., Belbahri L., Bouzid O., Broberg A.,
RA   Canback B., Coutinho P.M., Cullen D., Dalman K., Deflorio G.,
RA   van Diepen L.T., Dunand C., Duplessis S., Durling M., Gonthier P.,
RA   Grimwood J., Fossdal C.G., Hansson D., Henrissat B., Hietala A.,
RA   Himmelstrand K., Hoffmeister D., Hogberg N., James T.Y., Karlsson M.,
RA   Kohler A., Kues U., Lee Y.H., Lin Y.C., Lind M., Lindquist E.,
RA   Lombard V., Lucas S., Lunden K., Morin E., Murat C., Park J.,
RA   Raffaello T., Rouze P., Salamov A., Schmutz J., Solheim H.,
RA   Stahlberg J., Velez H., de Vries R.P., Wiebenga A., Woodward S.,
RA   Yakovlev I., Garbelotto M., Martin F., Grigoriev I.V., Stenlid J.;
RT   "Insight into trade-off between wood decay and parasitism from the
RT   genome of a fungal forest pathogen.";
RL   New Phytol. 194:1001-1013(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose
CC         residues in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|RuleBase:RU000675,
CC         ECO:0000256|SAAS:SAAS01116863};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|RuleBase:RU003679, ECO:0000256|SAAS:SAAS00534244}.
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DR   EMBL; KI925460; ETW79663.1; -; Genomic_DNA.
DR   RefSeq; XP_009548227.1; XM_009549932.1.
DR   EnsemblFungi; ETW79663; ETW79663; HETIRDRAFT_452773.
DR   GeneID; 20676296; -.
DR   KEGG; hir:HETIRDRAFT_452773; -.
DR   OrthoDB; 179316at2759; -.
DR   Proteomes; UP000030671; Unassembled WGS sequence.
DR   GO; GO:0048500; C:signal recognition particle; IEA:InterPro.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   Gene3D; 2.102.20.10; -; 1.
DR   Gene3D; 2.60.120.260; -; 2.
DR   Gene3D; 2.60.390.10; -; 1.
DR   Gene3D; 3.30.720.10; -; 1.
DR   InterPro; IPR018954; Betagal_dom2.
DR   InterPro; IPR037110; Betagal_dom2_sf.
DR   InterPro; IPR025972; BetaGal_dom3.
DR   InterPro; IPR036833; BetaGal_dom3_sf.
DR   InterPro; IPR025300; BetaGal_jelly_roll_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR019801; Glyco_hydro_35_CS.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR009018; Signal_recog_particle_SRP9/14.
DR   InterPro; IPR039432; SRP9_dom.
DR   PANTHER; PTHR23421; PTHR23421; 1.
DR   Pfam; PF10435; BetaGal_dom2; 1.
DR   Pfam; PF13363; BetaGal_dom3; 1.
DR   Pfam; PF13364; BetaGal_dom4_5; 2.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   Pfam; PF05486; SRP9-21; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SMART; SM01029; BetaGal_dom2; 1.
DR   SUPFAM; SSF117100; SSF117100; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   SUPFAM; SSF54762; SSF54762; 1.
DR   PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000030671};
KW   Glycosidase {ECO:0000256|RuleBase:RU000675,
KW   ECO:0000256|SAAS:SAAS00108888};
KW   Hydrolase {ECO:0000256|RuleBase:RU000675,
KW   ECO:0000256|SAAS:SAAS00108869, ECO:0000313|EMBL:ETW79663.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030671};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18   1123       Beta-galactosidase. {ECO:0000256|SAM:
FT                                SignalP}.
FT                                /FTId=PRO_5004844250.
FT   DOMAIN      382    566       BetaGal_dom2. {ECO:0000259|SMART:
FT                                SM01029}.
SQ   SEQUENCE   1123 AA;  122317 MW;  19DD82AA80284D3F CRC64;
     MLLDKLIVLA CTIGALAGPR KGNRKLRMSR ADHNDGLQDI VTWDEYSLKI NGERLYIFSG
     EVHPYRMPVQ SLHLDIFQKI KSLGFNAVSF YSFWGLHEPK RGEISFEGFR DLQPFIDAAL
     KAGIYLIARP GPYINAETTA GGFPGWGTYT PGVWRTSNTT YVDAYKGYMA AVGSIIAANE
     ITKGGPIILV QSENEYTGFA TGYSEDFEYE KELLQTLRDA GITVPTTHND ASPSGHYLSV
     NIYGYDSYPN GFDCSHPTTW KSNAVPENFW TTHERYNPQD LNAVYEFQGG AFDGWGGSGY
     DTCAVLLGPE FERVFYKNEL AMSTTLLSLY MIYGGTNWGG IAHPGVYTSY DYGSAIAEDR
     TLREKYYELK LQANFLKVSP AFLTTRPQNT GKTQGAFTGN QALKTTQTLD VVGNKTGFYV
     VRHTDSSSFD VQTYTLTVPT SNGTITFPQL GGSLTLTGKD SKIHVVDYEA GSTNILYSSA
     EILTWATVNG KDVILLYGNE GELHETALHF NGTAPTAKVV SGSGTVKQQA SSAGLVLQYT
     TTGQTVVEVG TSILLYILDR DNAYDFWVLN PPGTGAFANF NTKNPIIVKG GYFLRSVSVS
     GGTLSIQGDL NSTAAFEIIA PAASSKQVTF NGHGLALKKT SYGTLTATQA VQLPAITLPD
     LESITWKTSD SLPEIQAGYS DARWTVANHT TTVNPTQPKT PVVLYAGEYG YHTGNILWRA
     HFNSTGFVAE VWGGAAFGFS IWLDSTFLGS WEGDATHGSY TKTVSFPSAL TSGSPHVITI
     LQDHMGYEED WTAATDDFKN PRGLRSYSFV GSSSTNVSVW KVTGNLGGED YVDTTRGPLN
     EGGLFAERQG WHLPGFDDSK WQTGRPTDGI SQAGVGFYRT SFDLHVPSSV DYPMALVISN
     TTTNPHFRTQ FYVNGYQFGK YVNSIGPQKV FPVPQGILNY NGHNTLAVSL WAADAAGAKP
     GSLALQLTAK VQSSMEMPPR CLLLEAICVV MVYISTWQKY QEAAEALYAK SPKKARYCVK
     WKSSEGKLVL KITDDETCLK FKTHSSVFLG RFEALNLSLM QKMSNIRPPP PVPASVPRIT
     TASPAPLIKQ EDASADVPSS SVIPAAGGIA AAGVKKKKGK KRK
//
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