GenomeNet

Database: UniProt
Entry: W4K8N8_9HOMO
LinkDB: W4K8N8_9HOMO
Original site: W4K8N8_9HOMO 
ID   W4K8N8_9HOMO            Unreviewed;      1098 AA.
AC   W4K8N8;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   13-FEB-2019, entry version 24.
DE   SubName: Full=Glycoside hydrolase family 35 protein {ECO:0000313|EMBL:ETW81426.1};
GN   ORFNames=HETIRDRAFT_64765 {ECO:0000313|EMBL:ETW81426.1};
OS   Heterobasidion irregulare TC 32-1.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Agaricomycetes; Russulales; Bondarzewiaceae; Heterobasidion;
OC   Heterobasidion annosum species complex.
OX   NCBI_TaxID=747525 {ECO:0000313|EMBL:ETW81426.1, ECO:0000313|Proteomes:UP000030671};
RN   [1] {ECO:0000313|EMBL:ETW81426.1, ECO:0000313|Proteomes:UP000030671}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TC 32-1 {ECO:0000313|EMBL:ETW81426.1,
RC   ECO:0000313|Proteomes:UP000030671};
RX   PubMed=22463738; DOI=10.1111/j.1469-8137.2012.04128.x;
RA   Olson A., Aerts A., Asiegbu F., Belbahri L., Bouzid O., Broberg A.,
RA   Canback B., Coutinho P.M., Cullen D., Dalman K., Deflorio G.,
RA   van Diepen L.T., Dunand C., Duplessis S., Durling M., Gonthier P.,
RA   Grimwood J., Fossdal C.G., Hansson D., Henrissat B., Hietala A.,
RA   Himmelstrand K., Hoffmeister D., Hogberg N., James T.Y., Karlsson M.,
RA   Kohler A., Kues U., Lee Y.H., Lin Y.C., Lind M., Lindquist E.,
RA   Lombard V., Lucas S., Lunden K., Morin E., Murat C., Park J.,
RA   Raffaello T., Rouze P., Salamov A., Schmutz J., Solheim H.,
RA   Stahlberg J., Velez H., de Vries R.P., Wiebenga A., Woodward S.,
RA   Yakovlev I., Garbelotto M., Martin F., Grigoriev I.V., Stenlid J.;
RT   "Insight into trade-off between wood decay and parasitism from the
RT   genome of a fungal forest pathogen.";
RL   New Phytol. 194:1001-1013(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose
CC         residues in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|SAAS:SAAS01116863};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|RuleBase:RU003679, ECO:0000256|SAAS:SAAS00534244}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; KI925458; ETW81426.1; -; Genomic_DNA.
DR   RefSeq; XP_009545887.1; XM_009547592.1.
DR   EnsemblFungi; ETW81426; ETW81426; HETIRDRAFT_64765.
DR   GeneID; 20678699; -.
DR   KEGG; hir:HETIRDRAFT_64765; -.
DR   OrthoDB; 179316at2759; -.
DR   Proteomes; UP000030671; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.102.20.10; -; 1.
DR   Gene3D; 2.60.120.260; -; 2.
DR   Gene3D; 2.60.390.10; -; 1.
DR   InterPro; IPR018954; Betagal_dom2.
DR   InterPro; IPR037110; Betagal_dom2_sf.
DR   InterPro; IPR025972; BetaGal_dom3.
DR   InterPro; IPR036833; BetaGal_dom3_sf.
DR   InterPro; IPR025300; BetaGal_jelly_roll_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421; PTHR23421; 1.
DR   Pfam; PF10435; BetaGal_dom2; 1.
DR   Pfam; PF13363; BetaGal_dom3; 1.
DR   Pfam; PF13364; BetaGal_dom4_5; 2.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SMART; SM01029; BetaGal_dom2; 1.
DR   SUPFAM; SSF117100; SSF117100; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000030671};
KW   Glycosidase {ECO:0000256|SAAS:SAAS00108888};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00108869,
KW   ECO:0000313|EMBL:ETW81426.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030671};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     59     78       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      472    656       BetaGal_dom2. {ECO:0000259|SMART:
FT                                SM01029}.
SQ   SEQUENCE   1098 AA;  119298 MW;  F34CE966F7A198FE CRC64;
     MTWGAHQDSH ALDLKVDRDV VDAPLALRRK PGTRMPADRT EGSLNAYSVS SAIARRRSWS
     SWLLLGIASS LLTYVLLLPH SAPQIWSRSL DAAFDLSARY YSALADVNTV GDVALEPPRA
     LFSSNGRTDQ VQWDNYSLVL QGQRILIYSG EFHTYRLPVP SLWPDILQKV KAAGLNAISV
     YLHWGAINPA PGVIDFDGYR AVEPLYEAAK AAGIWIVLRP GPYINAETTA GGIAHWVTSE
     VAGPLRTNAT DFRASWQDYI QGVIEQTARY QITEGGPVIA IQIDNEYSQN AISGAYFSEL
     EEAYHNSSIV VPLTYNDPGE HKGFVNGSGA VDIYGLDAYP QGFDCSHPDT WSAVTTNYHD
     YHEGTNPSQP WYFPEFQGGS FDAWGPTAPG YENCRQLTGA SFESVFYRTL WASNAKLMSF
     YMLYGGTSWG GIPFPGVYTS YDYGSSIAEN RALTDKYTEL KLQGLFLRSS PEFYKTDWIG
     NSSTVVSVSN SAAFAVLLRN PDTRSSYWIV RQTSSTSTAT INFNMTIDTS AGTLQIPQVV
     SSITLSGRQS KVIVGDYSFG AHSSLLYSTA SILFAGKIGS RDVLFLYGDA DQEHEASLAT
     PGPASLRSDS PFVSFTPASG NQSVVSFLPG ISGLVTVFDT PSQLVLYADT VTAGTFWAPV
     LASTNAHANY WQIGTNSTLL VGGPHLVRNA SLSASGTLAL RGDLNSSVRL TVIGPPGVKR
     VTWNGEPVDP DTNAAERLTS VGGFTGQLAL KSAVQGIKTP VLRNWKFANS LPEADVGFDD
     SEWTVANHTT TNIPFKPFYG DGRVLYGCDY GFCENTVLWR GHFNGTADVK SANLSINGGE
     AFAASVWLND QFIGTSYGNS TNNRNILEET DDLFVFPNGS LLIGQDNVIT IVQDNMGLNE
     TESSPETSRS PRGVRGFKLN NGTFADWKVQ GKVGGYTNFP DKTRGVMNEG GLFGERKGWH
     LPGFDTSSWA SRSLSSGLPN DNAGVGFFVT TFDLRVPDGF DVLMSFNFDS TPAPYRALLF
     VNGWMMGKFV ANLGPQWKFP VHEGILEYQG TNTVAVALWA MESVLISPQL NVTIDAMLDG
     GVGNVVANNP PWTSRGRP
//
DBGET integrated database retrieval system