ID W4M949_9BACT Unreviewed; 304 AA.
AC W4M949;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Coenzyme PQQ synthesis protein B {ECO:0000256|ARBA:ARBA00015084, ECO:0000256|HAMAP-Rule:MF_00653};
DE AltName: Full=Pyrroloquinoline quinone biosynthesis protein B {ECO:0000256|HAMAP-Rule:MF_00653};
GN Name=pqqB {ECO:0000256|HAMAP-Rule:MF_00653};
GN ORFNames=ETSY2_14435 {ECO:0000313|EMBL:ETX06874.1};
OS Candidatus Entotheonella gemina.
OC Bacteria; Nitrospinae/Tectomicrobia group; Candidatus Tectomicrobia;
OC Entotheonella.
OX NCBI_TaxID=1429439 {ECO:0000313|EMBL:ETX06874.1, ECO:0000313|Proteomes:UP000019140};
RN [1] {ECO:0000313|EMBL:ETX06874.1, ECO:0000313|Proteomes:UP000019140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSY2 {ECO:0000313|Proteomes:UP000019140};
RX PubMed=24476823; DOI=10.1038/nature12959;
RA Wilson M.C., Mori T., Ruckert C., Uria A.R., Helf M.J., Takada K.,
RA Gernert C., Steffens U.A., Heycke N., Schmitt S., Rinke C., Helfrich E.J.,
RA Brachmann A.O., Gurgui C., Wakimoto T., Kracht M., Crusemann M.,
RA Hentschel U., Abe I., Matsunaga S., Kalinowski J., Takeyama H., Piel J.;
RT "An environmental bacterial taxon with a large and distinct metabolic
RT repertoire.";
RL Nature 506:58-62(2014).
CC -!- FUNCTION: May be involved in the transport of PQQ or its precursor to
CC the periplasm. {ECO:0000256|HAMAP-Rule:MF_00653}.
CC -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004886, ECO:0000256|HAMAP-Rule:MF_00653}.
CC -!- SIMILARITY: Belongs to the PqqB family. {ECO:0000256|ARBA:ARBA00008481,
CC ECO:0000256|HAMAP-Rule:MF_00653}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETX06874.1}.
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DR EMBL; AZHX01000580; ETX06874.1; -; Genomic_DNA.
DR AlphaFoldDB; W4M949; -.
DR PATRIC; fig|1429439.4.peg.2462; -.
DR HOGENOM; CLU_061120_0_0_7; -.
DR UniPathway; UPA00539; -.
DR Proteomes; UP000019140; Unassembled WGS sequence.
DR GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd16274; PQQB-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR HAMAP; MF_00653; PQQ_syn_PqqB; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR011842; PQQ_synth_PqqB.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR02108; PQQ_syn_pqqB; 1.
DR PANTHER; PTHR42663:SF7; COENZYME PQQ SYNTHESIS PROTEIN B; 1.
DR PANTHER; PTHR42663; HYDROLASE C777.06C-RELATED-RELATED; 1.
DR Pfam; PF12706; Lactamase_B_2; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW PQQ biosynthesis {ECO:0000256|ARBA:ARBA00022905, ECO:0000256|HAMAP-
KW Rule:MF_00653}; Reference proteome {ECO:0000313|Proteomes:UP000019140};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00653}.
FT DOMAIN 51..271
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF12706"
SQ SEQUENCE 304 AA; 33496 MW; D9FAA91E309B4589 CRC64;
MRIHVLGSAA GGGFPQWNCN CYNCHGLRRG EIKATARTQS SIAISGDGVG WVLTNASPDI
RTQLEAFPAM QPARAIRDTG ITGIVLMDSQ IDHTTGLLIL REGQPLDIYC TDMVHQDLTT
GNPLFNILGH YCGVNWHDIP LDEGDDFVVR GADQLRFHAV PLDSKAPPYS PHRHDPHLGD
NIGMWIEDDR TEKRLFYAPG LGHVDDRIRA YLAHADCLLV DGTFWRDDEL IQAGIVNKRA
RDMGHLAQSG PGGMISVLSD LERPRKILIH INNTNPILNE DSPERAALAD AGIEVAYDGM
DIEL
//
