GenomeNet

Database: UniProt
Entry: W4Q9G2_9BACI
LinkDB: W4Q9G2_9BACI
Original site: W4Q9G2_9BACI 
ID   W4Q9G2_9BACI            Unreviewed;       430 AA.
AC   W4Q9G2;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   05-JUN-2019, entry version 28.
DE   RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423};
DE            EC=2.3.1.- {ECO:0000256|RuleBase:RU003423};
GN   ORFNames=JCM9140_4210 {ECO:0000313|EMBL:GAE28024.1};
OS   Bacillus wakoensis JCM 9140.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1236970 {ECO:0000313|EMBL:GAE28024.1, ECO:0000313|Proteomes:UP000018890};
RN   [1] {ECO:0000313|EMBL:GAE28024.1, ECO:0000313|Proteomes:UP000018890}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 9140 {ECO:0000313|EMBL:GAE28024.1,
RC   ECO:0000313|Proteomes:UP000018890};
RA   Yuki M., Oshima K., Suda W., Oshida Y., Kitamura K., Iida T.,
RA   Hattori M., Ohkuma M.;
RT   "Draft Genome Sequences of Three Alkaliphilic Bacillus Strains,
RT   Bacillus wakoensis JCM 9140T, Bacillus akibai JCM 9157T, and Bacillus
RT   hemicellulosilyticus JCM 9152T.";
RL   Genome Announc. 2:e01258-13(2014).
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|RuleBase:RU003423};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003423}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAE28024.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; BAUT01000077; GAE28024.1; -; Genomic_DNA.
DR   RefSeq; WP_034750118.1; NZ_BAZN01000077.1.
DR   EnsemblBacteria; GAE28024; GAE28024; JCM9140_4210.
DR   OrthoDB; 1626282at2; -.
DR   Proteomes; UP000018890; Unassembled WGS sequence.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.559.10; -; 1.
DR   Gene3D; 4.10.320.10; -; 1.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF02817; E3_binding; 1.
DR   SUPFAM; SSF47005; SSF47005; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS00189; LIPOYL; 1.
DR   PROSITE; PS51826; PSBD; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003423};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018890};
KW   Lipoyl {ECO:0000256|RuleBase:RU003423, ECO:0000256|SAAS:SAAS00065550};
KW   Pyruvate {ECO:0000313|EMBL:GAE28024.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018890};
KW   Transferase {ECO:0000256|RuleBase:RU003423,
KW   ECO:0000313|EMBL:GAE28024.1}.
FT   DOMAIN        2     77       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
FT   DOMAIN      124    161       Peripheral subunit-binding (PSBD).
FT                                {ECO:0000259|PROSITE:PS51826}.
FT   REGION       81    119       Disordered. {ECO:0000256|MobiDB-lite:
FT                                W4Q9G2}.
FT   REGION      163    189       Disordered. {ECO:0000256|MobiDB-lite:
FT                                W4Q9G2}.
FT   COMPBIAS     81     95       Acidic. {ECO:0000256|MobiDB-lite:W4Q9G2}.
SQ   SEQUENCE   430 AA;  46128 MW;  2789BDC51D7C054F CRC64;
     MAYKFKLPDI GEGIHEGEIV KWFVKPGDEI KEDDILLEVQ NDKAVVEIPS PVDGKVLEVK
     VEEGTVSIVG DVLLTIDAGD ANTADEDEAE EATAESTKEE EVAKSSEPAA DTANDEVDND
     TRVIAMPSVR KYAREKGVAI QKVTGTGKNG RVVKEDIDTF LSGGAPAEAT ETTDAKEAPA
     ATAAAPQKSE PVAIPVGELE HRVPFKGVRK AIAKAMVNSK HTAPHVTHMD EIEVSNLVAH
     RKQYKELAAE QGTKLTYLPY VVKALTAALR KFPALNASID DANDEIVYKN YFNIGIAADT
     EHGLFVPVVK DADRKSIFAL ADEINELAAK ARDGKLSGAE MKGGSATISN VGSARGLWFT
     PVINHPEVAI LGIGRIEEKP VVKNGEIVAA PVLALSISYD HRLIDGVTAQ NALNHVKRLL
     NDPQLLLMEG
//
DBGET integrated database retrieval system