ID   W4QHX4_9BACI            Unreviewed;       609 AA.
AC   W4QHX4;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Bipolar DNA helicase {ECO:0000313|EMBL:GAE31730.1};
GN   ORFNames=JCM9152_3215 {ECO:0000313|EMBL:GAE31730.1};
OS   Halalkalibacter hemicellulosilyticusJCM 9152.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halalkalibacter.
OX   NCBI_TaxID=1236971 {ECO:0000313|EMBL:GAE31730.1, ECO:0000313|Proteomes:UP000018895};
RN   [1] {ECO:0000313|EMBL:GAE31730.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 9152 {ECO:0000313|EMBL:GAE31730.1};
RA   Yuki M., Oshima K., Suda W., Oshida Y., Kitamura K., Iida T., Hattori M.,
RA   Ohkuma M.;
RT   "Draft Genome Sequences of Three Alkaliphilic Bacillus Strains, Bacillus
RT   wakoensis JCM 9140T, Bacillus akibai JCM 9157T, and Bacillus
RT   hemicellulosilyticus JCM 9152T.";
RL   Genome Announc. 2:e01258-13(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAE31730.1}.
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DR   EMBL; BAUU01000023; GAE31730.1; -; Genomic_DNA.
DR   RefSeq; WP_035345761.1; NZ_BAZO01000023.1.
DR   AlphaFoldDB; W4QHX4; -.
DR   STRING; 1236971.JCM9152_3215; -.
DR   OrthoDB; 9806951at2; -.
DR   Proteomes; UP000018895; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR002789; HerA_central.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR42957; HELICASE MJ1565-RELATED; 1.
DR   PANTHER; PTHR42957:SF1; HELICASE MJ1565-RELATED; 1.
DR   Pfam; PF01935; DUF87; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:GAE31730.1};
KW   Helicase {ECO:0000313|EMBL:GAE31730.1};
KW   Hydrolase {ECO:0000313|EMBL:GAE31730.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000313|EMBL:GAE31730.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018895};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        371..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          156..293
FT                   /note="Helicase HerA central"
FT                   /evidence="ECO:0000259|Pfam:PF01935"
SQ   SEQUENCE   609 AA;  68916 MW;  FE9FEC3E20DA68AD CRC64;
     MQIVGVTTQH EVYVASKTHK FRMNEMLVIE DDSLYQPKGE VVETFSYNRY IPMGFDKGIA
     DDQVLKTLEQ IGYDIGSDDI HLAKARLFEE AIQPIQTGAQ VRHPHFEEIQ HLLVKAQPED
     GLILGEVKST DFISETLPSP LTGLLSIHDH HGLREQNGVP FIFDIRSMQQ YPHIGVFGGS
     GSGKSFGLRV MLEELMKLHI PSLVFDPHFE MNFAAQTEGI EGRSYEQNYT VVQIGKDVGV
     DFSALTTRDV ERLLAAAGSL TESMINVIQS IHKRKDSYQS FSDRIAHLAE ALEMGKQKVE
     GFLHDGGMTR EEMERYQLFK RLLDQYGSLP LASVKGIQWR VHRLHQAGLF QQNIRAIEEG
     MYAGKLVVVQ GAVWLLQVFS SYVIGALYGK RRAYRDAKLQ HMQGEFFPPF LVVTDEAHNF
     APKGFDAPAK SVLKEIAQEG RKYGVFLIFA TQRPTLLDET ITAQLNTKFV FRTVRGTDIQ
     TIKEETDLTA EEGKRLPYLR SGDAFVSSAI MGRTMAIRIR MAHSTSPHTL NPFDELEQMN
     AKGVDELISV LDEHLPFAEM DIMTLLPHLN TAAKKSWDVQ AWKKELERLS EDGYIKKEKT
     PFATMYTRS
//