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Database: UniProt
Entry: W4V2I1_9FIRM
LinkDB: W4V2I1_9FIRM
Original site: W4V2I1_9FIRM 
ID   W4V2I1_9FIRM            Unreviewed;       721 AA.
AC   W4V2I1;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   10-APR-2019, entry version 29.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   ORFNames=JCM21531_246 {ECO:0000313|EMBL:GAE86914.1};
OS   Hungateiclostridium straminisolvens JCM 21531.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales;
OC   Hungateiclostridiaceae; Hungateiclostridium.
OX   NCBI_TaxID=1294263 {ECO:0000313|EMBL:GAE86914.1, ECO:0000313|Proteomes:UP000019109};
RN   [1] {ECO:0000313|EMBL:GAE86914.1, ECO:0000313|Proteomes:UP000019109}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 21531 {ECO:0000313|EMBL:GAE86914.1,
RC   ECO:0000313|Proteomes:UP000019109};
RA   Yuki M., Oshima K., Suda W., Sakamoto M., Kitamura K., Iida T.,
RA   Hattori M., Ohkuma M.;
RT   "Draft Genome Sequence of Clostridium straminisolvens Strain JCM
RT   21531T, Isolated from a Cellulose-Degrading Bacterial Community.";
RL   Genome Announc. 2:e00110-14(2014).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAE86914.1}.
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DR   EMBL; BAVR01000002; GAE86914.1; -; Genomic_DNA.
DR   RefSeq; WP_038286691.1; NZ_BAVR01000002.1.
DR   EnsemblBacteria; GAE86914; GAE86914; JCM21531_246.
DR   OrthoDB; 304844at2; -.
DR   Proteomes; UP000019109; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000019109};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019109};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    282    307       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    394    412       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    424    448       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    454    474       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    517    534       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    546    564       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    614    633       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    645    668       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    674    695       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        2    163       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   721 AA;  78955 MW;  1910929FF82F9CDA CRC64;
     MSIKIALAGN PNSGKTTMFN DLTGSNQYVG NWPGVTVEKK EGKLKGHKDV IITDLPGIYS
     LSPYTPEEIV SRNYLINEKP DAIINIVDGT NIERNLYLTT QLTEMGIPVV IALNMIDIVR
     KKGDNIDIKK LSKKFGCDVI ETSALKGTGS KEAVSKAIAL AEQKVKTTPQ HKFSSSVEDS
     LSKIASYIEN SISPQLLRWY SIKLFERDQK VLEQLSLDEN IRTEIENIIA ECEKQLDDDS
     ESIITNERYK YIVDAIKDCY VRKNTSRETV SDKIDKIVTN RLLAFPIFAA VIFLVYFISV
     TTVGTWATDW VNDVLFGQII PPAVEGFLES VNCAGWLSSL IIDGIIGGVG AVLGFLPQMM
     VLFLCLSILE DCGYMARIAF IMDRVFRKFG LSGKSFIPII IGTGCGVPGV MASRTIESEE
     DRKLTIMTTT FIPCSAKLPI ISLIAGAFFP GSIWVAPSVY FIGIAAIICS GIILKKTKAL
     SSSPAPFVME LPAYHLPGIK NVAFQIWDKS KSFIKKAGTI IFLASGLVWF LSNFNWQLQM
     VDAQDSILAT LGGIVAPIFV PLGWGTWEAS VATLTGLVAK ENVVGTFGVL YGFHEVAEDG
     VEIWGSLQAS FTALSAYSLL IFNLLCAPCF AAIGAIRREM KSAKWTFIAI GYQTILAYAA
     SFCVYQLGML FMGNGFNVFT AIAILVVIGF IYLLLRRPYN KDAKNSSTKK VGKAMLGGAK
     L
//
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