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Database: UniProt
Entry: W4Z5B5_STRPU
LinkDB: W4Z5B5_STRPU
Original site: W4Z5B5_STRPU 
ID   W4Z5B5_STRPU            Unreviewed;       816 AA.
AC   W4Z5B5;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   28-FEB-2018, entry version 26.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_023320-tr};
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa;
OC   Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668 {ECO:0000313|EnsemblMetazoa:SPU_023320-tr, ECO:0000313|Proteomes:UP000007110};
RN   [1] {ECO:0000313|EnsemblMetazoa:SPU_023320-tr}
RP   NUCLEOTIDE SEQUENCE.
RA   Murali S., Liu Y., Vee V., English A., Wang M., Skinner E., Han Y.,
RA   Muzny D.M., Worley K.C., Gibbs R.A.;
RT   "Genome sequencing for Strongylocentrotus purpuratus.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SPU_023320-tr}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; AAGJ04153909; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7668.SPU_023320tr; -.
DR   EnsemblMetazoa; SPU_023320-tr; SPU_023320-tr; SPU_023320.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   OrthoDB; EOG09370FZV; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IBA:GO_Central.
DR   GO; GO:0006828; P:manganese ion transport; IBA:GO_Central.
DR   GO; GO:0051480; P:regulation of cytosolic calcium ion concentration; IBA:GO_Central.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   SUPFAM; SSF48403; SSF48403; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007110};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007110};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    315    338       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    350    371       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    377    400       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    412    433       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    439    461       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    473    494       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    556    580       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      180    232       TRP_2. {ECO:0000259|Pfam:PF08344}.
FT   DOMAIN      363    592       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   816 AA;  92893 MW;  2B94EA02A9F7A97A CRC64;
     MDMETVQTGE CFELKERNPS QDEESVDMSS RFEDVDKALF AAIEAGDEVA VEYILQAIKI
     NQLQRDFRDE IGRSTYDYVI EGGFVPILES LLDVGIPLGD ALLRSIAASW HEGTVFICNY
     VMTLPPEDRE SIYECRSRNA DFHPEMSPLK LVAMNNNFQI VEVLLKAGVS PLAKPQASQK
     STASLTDVVS LLDYYRAVSS EAYLGLAHPD PLDNAFRLSR KLRELGNDWE EFNAEFFRMA
     EKVERFSASL LNHLSSSVEL QTLFTQSSIP TRNPMSKVET AIAYQQKDFV AHAYSQKAMS
     FAFYQVFAST SNLRLVLMTS LLVIAYPFIS VVFLAYQGDV LTKLLRTPHI KLWMSFGSDV
     TLLICVALNS ILDKQDYTYP ILCVHVVILV HCIGLVWKHV QEIFSRGFIK FIKYYMNVAE
     VLIVTLCFGF VTSDWIGRLV VILCVFRTFH SVVTSYHAIF VIWKSTIGAI RDLVRFSAIL
     GGVLVSVAVG MNAMSLSEFY AQPSQCRNGL AVETCSIWDE RFITLPKSMS TLYWALFAVR
     GQTVRQSFGD DTVFALIYYV FFAAYFILAV VLGLNLFIAI MTSQLTKVQK NSDMEWKFGR
     AQLWLRVIEP VVELPPPFNL IPKSGTVQRM IKRWIGRETL SREEDEERPG DPERESMVLI
     HKLLERYQDQ KRESTPSCCG FTIEDFRILK ENFLSLRNHI SKILRLIEMS IESLEVVVEG
     LNIRIGKLND TDTQLDGIDH NRVQIEDDDI DQLTDDVTNL EKCVRHAMAR LQSTSLITQM
     AEMYSQGRTV VNDDEARGKL ESYRQDFDSY ATNLYA
//
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