ID W5CV95_WHEAT Unreviewed; 642 AA.
AC W5CV95;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Cysteine-rich receptor-like protein kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_039299 {ECO:0000313|EMBL:KAF7027238.1},
GN TRAES_3BF091400080CFD_c1 {ECO:0000313|EMBL:CDM80709.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EMBL:CDM80709.1};
RN [1] {ECO:0000313|EMBL:CDM80709.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25035497; DOI=10.1126/science.1249721;
RA Choulet F., Alberti A., Theil S., Glover N., Barbe V., Daron J.,
RA Pingault L., Sourdille P., Couloux A., Paux E., Leroy P., Mangenot S.,
RA Guilhot N., Le Gouis J., Balfourier F., Alaux M., Jamilloux V., Poulain J.,
RA Durand C., Bellec A., Gaspin C., Safar J., Dolezel J., Rogers J.,
RA Vandepoele K., Aury J.M., Mayer K., Berges H., Quesneville H., Wincker P.,
RA Feuillet C.;
RT "Structural and functional partitioning of bread wheat chromosome 3B.";
RL Science 345:1249721-1249721(2014).
RN [2] {ECO:0000313|EMBL:KAF7027238.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7027238.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3B02G044200.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3B02G044200.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [4] {ECO:0000313|EnsemblPlants:TraesCS3B02G044200.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [5] {ECO:0000313|EMBL:KAF7027238.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7027238.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; HG670306; CDM80709.1; -; Genomic_DNA.
DR EMBL; CM022218; KAF7027238.1; -; Genomic_DNA.
DR SMR; W5CV95; -.
DR STRING; 4565.W5CV95; -.
DR PaxDb; 4565-Traes_3B_55B9E8C9D-1; -.
DR EnsemblPlants; TraesCS3B02G044200.1; TraesCS3B02G044200.1; TraesCS3B02G044200.
DR Gramene; TraesCS3B02G044200.1; TraesCS3B02G044200.1; TraesCS3B02G044200.
DR Gramene; TraesCS3B03G0100800.1; TraesCS3B03G0100800.1.CDS; TraesCS3B03G0100800.
DR Gramene; TraesKAR3B01G0019800.1; cds.TraesKAR3B01G0019800.1; TraesKAR3B01G0019800.
DR Gramene; TraesWEE_scaffold_001629_01G000600.1; TraesWEE_scaffold_001629_01G000600.1; TraesWEE_scaffold_001629_01G000600.
DR eggNOG; ENOG502QWDY; Eukaryota.
DR HOGENOM; CLU_000288_35_3_1; -.
DR OMA; KSHSAEM; -.
DR OrthoDB; 362416at2759; -.
DR Proteomes; UP000019116; Chromosome 3B.
DR Proteomes; UP000815260; Chromosome 3B.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.30.430.20; Gnk2 domain, C-X8-C-X2-C motif; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002902; GNK2.
DR InterPro; IPR038408; GNK2_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27002:SF902; -; 1.
DR PANTHER; PTHR27002; RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE SD1-8; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF01657; Stress-antifung; 2.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51473; GNK2; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..642
FT /note="Cysteine-rich receptor-like protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014594570"
FT TRANSMEM 262..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..116
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 125..236
FT /note="Gnk2-homologous"
FT /evidence="ECO:0000259|PROSITE:PS51473"
FT DOMAIN 325..602
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 353
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 642 AA; 70248 MW; 463543E7E429299C CRC64;
MATTGVVILL LLLLAPTPYL AAADFCDNVK AAGAALSRNA SSSPVQFSTA TIGQAPDVVY
ALALCLGDVL DGSACGACIA DWFATVNQTQ CDKAGSSYRD CIVVYGATAD ILAAPSNATG
GYGDNTPPFQ DWNIRNVTAD DAPRIVNLTF ELLAKTAQMA ATATPKLYAT GVMAMKRVTT
YPDVYSQVQC TPDLSADDCS ACLSRLLRMV NSTMALRMGG RMGVTRCFFR YEAFPLYGAR
PMLSLPSSPP GPAPTPTKRR SMLWVIPVAL VPLTAAALLF FICYRRRLTR QRKGSRRAHS
LEWQGKNSDF SLFEFEHLLE ATRNFSEESK LGQGGFGAVY KGQLSDGSEI AVKRLASHSG
QGFMEFKNEV QLIAKLQHMN LVRLLGCCSQ EEEKILVYEY LPNKSLDFFI FDENKRALLD
WTNLAVIIEG VANGLLYLHK HSRLLVIHRD LKPSNILLDC EMNPKISDFG LAKIFSSNDT
EGDITRRVVG TYGYMAPEYA SKGNFSIKSD VFSFGVVILE ILSGKRNSGT QQCGGFINLL
GYAWQLWVEG KWIDLVDASL VSDSHSTKIM RCINIALLCV QENAVDRPTM GDIVSMLSNE
TMILADPKQP AYINVRVGNE ETSNAPESYS INDVSISITS PR
//
