ID W5CXE5_WHEAT Unreviewed; 352 AA.
AC W5CXE5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=CFC21_043266 {ECO:0000313|EMBL:KAF7032038.1},
GN TRAES_3BF032000110CFD_c1 {ECO:0000313|EMBL:CDM85416.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EMBL:CDM85416.1};
RN [1] {ECO:0000313|EMBL:CDM85416.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25035497; DOI=10.1126/science.1249721;
RA Choulet F., Alberti A., Theil S., Glover N., Barbe V., Daron J.,
RA Pingault L., Sourdille P., Couloux A., Paux E., Leroy P., Mangenot S.,
RA Guilhot N., Le Gouis J., Balfourier F., Alaux M., Jamilloux V., Poulain J.,
RA Durand C., Bellec A., Gaspin C., Safar J., Dolezel J., Rogers J.,
RA Vandepoele K., Aury J.M., Mayer K., Berges H., Quesneville H., Wincker P.,
RA Feuillet C.;
RT "Structural and functional partitioning of bread wheat chromosome 3B.";
RL Science 345:1249721-1249721(2014).
RN [2] {ECO:0000313|EMBL:KAF7032038.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7032038.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3B02G434300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3B02G434300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [4] {ECO:0000313|EnsemblPlants:TraesCS3B02G434300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [5] {ECO:0000313|EMBL:KAF7032038.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7032038.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
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DR EMBL; HG670306; CDM85416.1; -; Genomic_DNA.
DR EMBL; CM022218; KAF7032038.1; -; Genomic_DNA.
DR SMR; W5CXE5; -.
DR STRING; 4565.W5CXE5; -.
DR PaxDb; 4565-Traes_3B_7239BE974-2; -.
DR EnsemblPlants; TraesCS3B02G434300.1; TraesCS3B02G434300.1; TraesCS3B02G434300.
DR Gramene; TraesCAD_scaffold_081054_01G000100.1; TraesCAD_scaffold_081054_01G000100.1; TraesCAD_scaffold_081054_01G000100.
DR Gramene; TraesCLE_scaffold_003765_01G000800.1; TraesCLE_scaffold_003765_01G000800.1; TraesCLE_scaffold_003765_01G000800.
DR Gramene; TraesCS3B02G434300.1; TraesCS3B02G434300.1; TraesCS3B02G434300.
DR Gramene; TraesCS3B03G1072100.1; TraesCS3B03G1072100.1.CDS; TraesCS3B03G1072100.
DR Gramene; TraesKAR3B01G0446990.1; cds.TraesKAR3B01G0446990.1; TraesKAR3B01G0446990.
DR Gramene; TraesPAR_scaffold_081429_01G000400.1; TraesPAR_scaffold_081429_01G000400.1; TraesPAR_scaffold_081429_01G000400.
DR Gramene; TraesROB_scaffold_079627_01G000300.1; TraesROB_scaffold_079627_01G000300.1; TraesROB_scaffold_079627_01G000300.
DR Gramene; TraesWEE_scaffold_084710_01G000100.1; TraesWEE_scaffold_084710_01G000100.1; TraesWEE_scaffold_084710_01G000100.
DR eggNOG; KOG1196; Eukaryota.
DR HOGENOM; CLU_026673_29_1_1; -.
DR OMA; EEKCRYA; -.
DR OrthoDB; 179761at2759; -.
DR Proteomes; UP000019116; Chromosome 3B.
DR Proteomes; UP000815260; Chromosome 3B.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd08295; double_bond_reductase_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF35; ZINC-BINDING DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 32..347
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 352 AA; 38442 MW; 7FF4150EFCCDE5C5 CRC64;
MEQANPPAGS ARNRKVVLRE YISRAPREDD MALVDGGAMP LRVPEGAAGP AVLVKNLYLS
CDPYMRGRMR DFHGSYIPPF KPGSVIEGLG VARVMDSTHP GFVAGDIVSG MTGWEEYSLI
DKPEQLNKIQ QSDIPLSYHL GLLGMPGFTA YVGFYEICSP KKGEFVFVSA ASGAVGQIVG
QLAKLHGCYV VGSAGTNEKV ELLKDKFGFD AAFNYKEEPD LTVALKRYFP EGIDIYFENV
GGPMLDAVLL NMRMHGRIAV CGMVSQHGMT DPAGIHNLFC LVPKRISMKG FIQSDYINLF
PQFVDYMTKH YKDGKIAYVE DMSIGLENAP AAFVGLFSGK NVGKQVVCVS QE
//
