ID W5DXV3_WHEAT Unreviewed; 321 AA.
AC W5DXV3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273};
DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};
GN ORFNames=CFC21_051743 {ECO:0000313|EMBL:KAF7042041.1}, CFC21_062159
GN {ECO:0000313|EMBL:KAF7054495.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4A02G093600.1};
RN [1] {ECO:0000313|EMBL:KAF7042041.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7042041.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4A02G093600.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4A02G093600.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4A02G093600.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7042041.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7042041.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|RuleBase:RU004273};
CC -!- SIMILARITY: Belongs to the PPP phosphatase family.
CC {ECO:0000256|RuleBase:RU004273}.
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DR EMBL; CM022220; KAF7042041.1; -; Genomic_DNA.
DR EMBL; CM022222; KAF7054495.1; -; Genomic_DNA.
DR SMR; W5DXV3; -.
DR STRING; 4565.W5DXV3; -.
DR PaxDb; 4565-Traes_4AS_6D7CDA716-1; -.
DR EnsemblPlants; TraesCS4A02G093600.1; TraesCS4A02G093600.1; TraesCS4A02G093600.
DR EnsemblPlants; TraesCS4D02G211500.1; TraesCS4D02G211500.1; TraesCS4D02G211500.
DR Gramene; TraesCS4A02G093600.1; TraesCS4A02G093600.1; TraesCS4A02G093600.
DR Gramene; TraesCS4A03G0192300.1; TraesCS4A03G0192300.1.CDS; TraesCS4A03G0192300.
DR Gramene; TraesCS4D02G211500.1; TraesCS4D02G211500.1; TraesCS4D02G211500.
DR Gramene; TraesCS4D03G0516500.1; TraesCS4D03G0516500.1.CDS; TraesCS4D03G0516500.
DR Gramene; TraesKAR4D01G0261090.1; cds.TraesKAR4D01G0261090.1; TraesKAR4D01G0261090.
DR Gramene; TraesPAR_scaffold_055442_01G000100.1; TraesPAR_scaffold_055442_01G000100.1; TraesPAR_scaffold_055442_01G000100.
DR Gramene; TraesRN4A0100193900.1; TraesRN4A0100193900.1; TraesRN4A0100193900.
DR Gramene; TraesRN4D0100534800.1; TraesRN4D0100534800.1; TraesRN4D0100534800.
DR eggNOG; KOG0374; Eukaryota.
DR HOGENOM; CLU_004962_0_0_1; -.
DR OMA; EEHEIRY; -.
DR OrthoDB; 5484004at2759; -.
DR Proteomes; UP000019116; Chromosome 4A.
DR Proteomes; UP000019116; Chromosome 4D.
DR Proteomes; UP000815260; Chromosome 4A.
DR Proteomes; UP000815260; Chromosome 4D.
DR ExpressionAtlas; W5DXV3; baseline.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IBA:GO_Central.
DR CDD; cd07414; MPP_PP1_PPKL; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR InterPro; IPR031675; STPPase_N.
DR PANTHER; PTHR11668; SERINE/THREONINE PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR11668:SF459; SERINE_THREONINE-PROTEIN PHOSPHATASE PP1 ISOZYME 2-RELATED; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16891; STPPase_N; 1.
DR PRINTS; PR00114; STPHPHTASE.
DR SMART; SM00156; PP2Ac; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004273};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 131..136
FT /note="Serine/threonine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS00125"
SQ SEQUENCE 321 AA; 36171 MW; 0ED353DF871300FF CRC64;
MAAAPAAGGQ GGGMDAALLD DIIRRLLEVR TARPGKQVQL SESEIRQLCT ASRDIFLTQP
NLLELEAPIK ICGDIHGQYS DLLRLFEYGG FPPEANYLFL GDYVDRGKQS LETICLLLAY
KIKYPENFFL LRGNHECASI NRIYGFYDEC KRRFNVRLWK VFTDCFNCLP VAALIDDKIL
CMHGGLSPDL GHLDEIKNLP RPTDVPDTGL LCDLLWSDPG KDVQGWGMND RGVSYTFGHD
KVTEFLLKHD LDLICRAHQV VEDGYEFFAD RQLVTIFSAP NYCGEFDNAG AMMSVDETLM
CSFQILKPAE RKIKFMASNK M
//
