ID W5J443_ANODA Unreviewed; 241 AA.
AC W5J443;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Bax inhibitor {ECO:0000313|EMBL:ETN58113.1};
GN ORFNames=AND_010314 {ECO:0000313|EMBL:ETN58113.1};
OS Anopheles darlingi (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43151 {ECO:0000313|EMBL:ETN58113.1};
RN [1] {ECO:0000313|EMBL:ETN58113.1, ECO:0000313|Proteomes:UP000000673}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20920257; DOI=10.1186/1471-2164-11-529;
RA Mendes N.D., Freitas A.T., Vasconcelos A.T., Sagot M.F.;
RT "Combination of measures distinguishes pre-miRNAs from other stem-loops in
RT the genome of the newly sequenced Anopheles darlingi.";
RL BMC Genomics 11:529-529(2010).
RN [2] {ECO:0000313|EMBL:ETN58113.1}
RP NUCLEOTIDE SEQUENCE.
RA Almeida L.G., Nicolas M.F., Souza R.C., Vasconcelos A.T.R.;
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ETN58113.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23761445;
RA Marinotti O., Cerqueira G.C., de Almeida L.G., Ferro M.I., Loreto E.L.,
RA Zaha A., Teixeira S.M., Wespiser A.R., Almeida E Silva A.,
RA Schlindwein A.D., Pacheco A.C., Silva A.L., Graveley B.R., Walenz B.P.,
RA Lima Bde A., Ribeiro C.A., Nunes-Silva C.G., de Carvalho C.R., Soares C.M.,
RA de Menezes C.B., Matiolli C., Caffrey D., Araujo D.A., de Oliveira D.M.,
RA Golenbock D., Grisard E.C., Fantinatti-Garboggini F., de Carvalho F.M.,
RA Barcellos F.G., Prosdocimi F., May G., Azevedo Junior G.M., Guimaraes G.M.,
RA Goldman G.H., Padilha I.Q., Batista Jda S., Ferro J.A., Ribeiro J.M.,
RA Fietto J.L., Dabbas K.M., Cerdeira L., Agnez-Lima L.F., Brocchi M.,
RA de Carvalho M.O., Teixeira Mde M., Diniz Maia Mde M., Goldman M.H.,
RA Cruz Schneider M.P., Felipe M.S., Hungria M., Nicolas M.F., Pereira M.,
RA Montes M.A., Cantao M.E., Vincentz M., Rafael M.S., Silverman N.,
RA Stoco P.H., Souza R.C., Vicentini R., Gazzinelli R.T., Neves Rde O.,
RA Silva R., Astolfi-Filho S., Maciel T.E., Urmenyi T.P., Tadei W.P.,
RA Camargo E.P., de Vasconcelos A.T.;
RT "The genome of Anopheles darlingi, the main neotropical malaria vector.";
RL Nucleic Acids Res. 41:7387-7400(2013).
RN [4] {ECO:0000313|EnsemblMetazoa:ADAC010314-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000256|RuleBase:RU004379}.
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DR EMBL; ADMH02002165; ETN58113.1; -; Genomic_DNA.
DR AlphaFoldDB; W5J443; -.
DR STRING; 43151.W5J443; -.
DR EnsemblMetazoa; ADAC010314-RA; ADAC010314-PA; ADAC010314.
DR VEuPathDB; VectorBase:ADAC010314; -.
DR VEuPathDB; VectorBase:ADAR2_010742; -.
DR eggNOG; KOG1629; Eukaryota.
DR HOGENOM; CLU_061277_0_0_1; -.
DR OMA; EPPVRQH; -.
DR OrthoDB; 5487825at2759; -.
DR Proteomes; UP000000673; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd10430; BI-1; 1.
DR InterPro; IPR006214; Bax_inhibitor_1-related.
DR PANTHER; PTHR23291:SF122; BAX INHIBITOR 1; 1.
DR PANTHER; PTHR23291; BAX INHIBITOR-RELATED; 1.
DR Pfam; PF01027; Bax1-I; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004379};
KW Reference proteome {ECO:0000313|Proteomes:UP000000673};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU004379};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU004379}.
FT TRANSMEM 55..74
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 114..135
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 142..161
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 173..190
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
SQ SEQUENCE 241 AA; 26835 MW; F6142A5F8DC465E1 CRC64;
MATSFANFSF ERLTQQMGAK LDPRLREHLS KVYGCLAATC GMATVGSYIH LSGLWQAGLL
SGLISLGLVL GLLFTPDNGK NLPQRFGMLM GIGMFTGHSL GLLLQYVIYL NPAIVVTALV
GTVTIFSCLT AAAFFAKRGS YLYLGGMLMS ALSMMALMNL GNLFFRSYFV HDINLYLGLL
VMSGFILFDT QMIMEKHHMG SNDFIGHSLD LFYDVINVFR RLLMILAQKE ENNERRKRKN
N
//
