ID W5JUQ5_ANODA Unreviewed; 670 AA.
AC W5JUQ5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=EF-hand domain-containing protein 1 {ECO:0000313|EMBL:ETN66484.1};
GN ORFNames=AND_001717 {ECO:0000313|EMBL:ETN66484.1};
OS Anopheles darlingi (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43151 {ECO:0000313|EMBL:ETN66484.1};
RN [1] {ECO:0000313|EMBL:ETN66484.1, ECO:0000313|Proteomes:UP000000673}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20920257; DOI=10.1186/1471-2164-11-529;
RA Mendes N.D., Freitas A.T., Vasconcelos A.T., Sagot M.F.;
RT "Combination of measures distinguishes pre-miRNAs from other stem-loops in
RT the genome of the newly sequenced Anopheles darlingi.";
RL BMC Genomics 11:529-529(2010).
RN [2] {ECO:0000313|EMBL:ETN66484.1}
RP NUCLEOTIDE SEQUENCE.
RA Almeida L.G., Nicolas M.F., Souza R.C., Vasconcelos A.T.R.;
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ETN66484.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23761445;
RA Marinotti O., Cerqueira G.C., de Almeida L.G., Ferro M.I., Loreto E.L.,
RA Zaha A., Teixeira S.M., Wespiser A.R., Almeida E Silva A.,
RA Schlindwein A.D., Pacheco A.C., Silva A.L., Graveley B.R., Walenz B.P.,
RA Lima Bde A., Ribeiro C.A., Nunes-Silva C.G., de Carvalho C.R., Soares C.M.,
RA de Menezes C.B., Matiolli C., Caffrey D., Araujo D.A., de Oliveira D.M.,
RA Golenbock D., Grisard E.C., Fantinatti-Garboggini F., de Carvalho F.M.,
RA Barcellos F.G., Prosdocimi F., May G., Azevedo Junior G.M., Guimaraes G.M.,
RA Goldman G.H., Padilha I.Q., Batista Jda S., Ferro J.A., Ribeiro J.M.,
RA Fietto J.L., Dabbas K.M., Cerdeira L., Agnez-Lima L.F., Brocchi M.,
RA de Carvalho M.O., Teixeira Mde M., Diniz Maia Mde M., Goldman M.H.,
RA Cruz Schneider M.P., Felipe M.S., Hungria M., Nicolas M.F., Pereira M.,
RA Montes M.A., Cantao M.E., Vincentz M., Rafael M.S., Silverman N.,
RA Stoco P.H., Souza R.C., Vicentini R., Gazzinelli R.T., Neves Rde O.,
RA Silva R., Astolfi-Filho S., Maciel T.E., Urmenyi T.P., Tadei W.P.,
RA Camargo E.P., de Vasconcelos A.T.;
RT "The genome of Anopheles darlingi, the main neotropical malaria vector.";
RL Nucleic Acids Res. 41:7387-7400(2013).
RN [4] {ECO:0000313|EnsemblMetazoa:ADAC001717-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
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DR EMBL; ADMH02000438; ETN66484.1; -; Genomic_DNA.
DR AlphaFoldDB; W5JUQ5; -.
DR STRING; 43151.W5JUQ5; -.
DR EnsemblMetazoa; ADAC001717-RA; ADAC001717-PA; ADAC001717.
DR VEuPathDB; VectorBase:ADAC001717; -.
DR VEuPathDB; VectorBase:ADAR2_009386; -.
DR eggNOG; KOG0043; Eukaryota.
DR HOGENOM; CLU_018366_0_0_1; -.
DR OMA; RYSARMD; -.
DR OrthoDB; 160134at2759; -.
DR Proteomes; UP000000673; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 2.30.29.170; -; 3.
DR InterPro; IPR006602; DM10_dom.
DR InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12086:SF9; EF-HAND DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF06565; DM10_dom; 3.
DR SMART; SM00676; DM10; 3.
DR PROSITE; PS51336; DM10; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000000673}.
FT DOMAIN 91..197
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 243..364
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 421..525
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT REGION 583..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..634
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..670
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 77283 MW; 41C132DE6D70BDF3 CRC64;
MEGLPKLPGN DFANRLRQKH HVPQSFKYIN GYPIPVRPEC GLGGERLNED SIQFCPGDSS
NDTVLYDPIL TYGRVRHLPV KPYRPHFVLY DQKTLNFRAF FRQAVPESAT ETFRIRYVNI
LYFLEDDTMT VLEPTIENCG YPQGRLVRRG KKLRNEDRGE FYTWKDLNIG INVEMHGYVF
HITDCDAYTK EFLLSNGIEL NEIELLPPDP AMNERSIAQR QTFRHHKMYP EPDDKLRKYL
EYQGKVLHFD CVLDERDREG GGELMTYKLF YYLEDDTVSI KELKENQEGR DYFPMLLRKQ
KLPKNWKDNP VSYPSIFLEK TDHEVSEYHS PKDLIVGTTL FVYGRKFLLL DCDGFTRSYY
EKALKIVQPD RVTLAAPEPR TPRLDVPLYL GLGTPEDSLA SHHSLVPKSP KKDVVTYLVN
VNKFLRYGCV LDTAHPEDKI RRFVLSLSLA DGTISIMESA IDNSGIRGGR FLSPRKIWLP
DCNPNEPSYY TAKDLYIGAT IVVFAHRFRI VSADLYVYRY MQAHPEMFAP NAIESVRDYL
LTEGHLREDL RQATDTEYQK LAETAKPTDA GEAATDEVKR RLTGFEISEP SRPVSPLAPE
RTESPRLPSP TMKHPCPHPI IPDEEIRKAY HTNEPEELAI QANRPNDTPT QPESPAHDAK
GKKTVRFLED
//
