ID W5JZ47_ASTMX Unreviewed; 706 AA.
AC W5JZ47;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Adenylate kinase 7 {ECO:0000313|Ensembl:ENSAMXP00000000607.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000000607.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000000607.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; W5JZ47; -.
DR STRING; 7994.ENSAMXP00000000607; -.
DR Ensembl; ENSAMXT00000000607.2; ENSAMXP00000000607.2; ENSAMXG00000000582.2.
DR eggNOG; KOG3078; Eukaryota.
DR GeneTree; ENSGT00390000015102; -.
DR HOGENOM; CLU_015567_1_0_1; -.
DR InParanoid; W5JZ47; -.
DR OrthoDB; 5483389at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000000582; Expressed in head kidney and 6 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01428; ADK; 1.
DR CDD; cd22967; DD_AK7; 1.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR047499; DD_AK7.
DR InterPro; IPR007858; Dpy-30_motif.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23359:SF105; ADENYLATE KINASE 7; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00406; ADK; 1.
DR Pfam; PF05186; Dpy-30; 1.
DR PRINTS; PR00094; ADENYLTKNASE.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT COILED 611..658
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 706 AA; 80495 MW; 58F2015E14CC4D45 CRC64;
MAQEAAGRAR LYNRIYINNI HSYSSKHISQ YLSSCRFGAS LVDPEVDERE GVQDDQTNEA
KAKEGTFQIV GTTSGKAEQK CSFAAAEYNN LTQTELLHHL MECDVIFYNI TEHADQIAEA
SWAVSALHKE IDEFTGPKMF ILISTVMTWA LSKPVDPDDP EIPFTEEDYR RRKAHPNFKD
HIALEKLVVK LGKTNRSQFC TYVVAAGLQY GLEEQVFHLF FKKAWLGEAG GVPVFGDGSN
IVPTVHVTDL ARIVQNIIDR KPNPQYFLAV DDSKHTMEEI VRAIANNLGS GKTQTVPKDD
LYLTQDLTQA DIDSLFVSLR MEAAFLKENF NMRWISETGI VENIERVTEE YKLSRGLLPV
RICLLGPPAV GKSTVAEKIC KHYKLHHVRL KETIAETLAN LEAGIYQDEG ENEGAESSGG
AQEFLETLRE NMEQNGGLLD DQFIIQIMKD KLKSKPCTNQ GFVLDGFPKT YDQAKELFSA
EEDELEDARS KIPPHNKKII PEFIFSLDAT DAFLKKRVLN LPESVVEGTS YSQEKFLRRL
ASFRENNSED ETVLNFFDEL EIPLEHIEIT SSDDLDYLLV MEKVSKCVGQ PRNYGPSSEE
VELEERRQVE IRIREEAALQ AEMERNEAEE AAQRTQKWEE WSRRLEEIQR QEDELLEAES
VPLRQYLMRD VMPTLTQGLI ECCRIRPEDP VDFLAEYLLK NNPEAE
//
