ID W5K1I0_ASTMX Unreviewed; 249 AA.
AC W5K1I0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Transmembrane protein 150A-like {ECO:0000313|Ensembl:ENSAMXP00000001440.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000001440.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000001440.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the DRAM/TMEM150 family.
CC {ECO:0000256|ARBA:ARBA00006565}.
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DR RefSeq; XP_007240331.1; XM_007240269.2.
DR AlphaFoldDB; W5K1I0; -.
DR Ensembl; ENSAMXT00000001440.2; ENSAMXP00000001440.2; ENSAMXG00000001412.2.
DR GeneID; 103032322; -.
DR KEGG; amex:103032322; -.
DR eggNOG; KOG4320; Eukaryota.
DR GeneTree; ENSGT01030000234578; -.
DR HOGENOM; CLU_059992_1_0_1; -.
DR InParanoid; W5K1I0; -.
DR OrthoDB; 3919361at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000001412; Expressed in pharyngeal gill and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR019402; Frag1/DRAM/Sfk1.
DR PANTHER; PTHR21324; FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED; 1.
DR PANTHER; PTHR21324:SF13; TRANSMEMBRANE PROTEIN 150-LIKE PRECURSOR; 1.
DR Pfam; PF10277; Frag1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 5..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 249 AA; 27678 MW; A2742549CC7433D9 CRC64;
MGLWIILPIT LSAVSFIGCW VVYGLAVSFN HVCPLSNWEY KNSCLTNETE FCCTDNNVPT
ISTSGTYFPE NSLFSATINA GSFLFLIFCI FHHAHIVDRS IANSLLSKFA MVFGCIAAIG
AFVAGNCNPA ELVLLHYLGA ALSFVCICFY TVLLTSLTSR CGLTGMESFL YPLRIVSTSI
QVVVTILYCI FFVQTSYYFK HLSAVFEWTL SANLELFELS YAVEFYCFSS AMLSVLLERR
GEEKPLILS
//
