ID W5KB10_ASTMX Unreviewed; 99 AA.
AC W5KB10;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Transmembrane protein 91 {ECO:0000313|Ensembl:ENSAMXP00000004771.2};
GN Name=TMEM91 {ECO:0000313|Ensembl:ENSAMXP00000004771.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000004771.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000004771.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CD225/Dispanin family.
CC {ECO:0000256|ARBA:ARBA00006843}.
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DR AlphaFoldDB; W5KB10; -.
DR STRING; 7994.ENSAMXP00000004771; -.
DR Ensembl; ENSAMXT00000004771.2; ENSAMXP00000004771.2; ENSAMXG00000004664.2.
DR eggNOG; ENOG502RXDR; Eukaryota.
DR GeneTree; ENSGT00950000183147; -.
DR HOGENOM; CLU_094250_0_0_1; -.
DR InParanoid; W5KB10; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000004664; Expressed in camera-type eye and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007593; CD225/Dispanin_fam.
DR PANTHER; PTHR14768:SF2; TRANSMEMBRANE PROTEIN 91; 1.
DR PANTHER; PTHR14768; UPF0338 PROTEIN; 1.
DR Pfam; PF04505; CD225; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 99 AA; 10718 MW; DC4F6F1F5218443C CRC64;
SSSDDFSDTD SESNFPLMIP QDYLGLAFFS MLCCFWPLGI AAFYLSQKTN KASAQGDFQG
ASTASRQALW LSILSIIFGI ITYICAIAAL ISYLSGKPP
//
