ID W5KIY2_ASTMX Unreviewed; 442 AA.
AC W5KIY2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Uncharacterized LOC103029795 {ECO:0000313|Ensembl:ENSAMXP00000007544.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000007544.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000007544.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5KIY2; -.
DR STRING; 7994.ENSAMXP00000007544; -.
DR Ensembl; ENSAMXT00000007544.2; ENSAMXP00000007544.2; ENSAMXG00000007344.2.
DR eggNOG; ENOG502SAU0; Eukaryota.
DR GeneTree; ENSGT00390000012668; -.
DR HOGENOM; CLU_618137_0_0_1; -.
DR InParanoid; W5KIY2; -.
DR OrthoDB; 4273868at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000007344; Expressed in olfactory epithelium and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF50; INTERLEUKIN-10 RECEPTOR SUBUNIT BETA; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..442
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017277036"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..121
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 409..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..426
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 442 AA; 49698 MW; C95018C6846011E7 CRC64;
MRSLPVSVLT LLLIYITSAE GALNAPLNLS VVLLDFRASI YWLPGPWNPI GTRYSVEFIE
VQNFSKTVWK KPAGCSNITE RQCHLFPDQF FENYFVRVMA EWKDERSNWT ILEHTFQPYK
DTQLSSPEMK ISPTHHSIHI RLSHKIQAVY QDVPLRFNVD LFRMTSSKTV EHIGKSKNTG
VFNFSNLPSG YSYCINASAF HTEMSIIQNL NATGCIFLQQ GPRGVIVGVG VLLLLVISAG
IILSAKGLLR TLIKDGYFPK VLLIKGGTAA PQTLNVETPC VHPLSVSDYP QVIESTHDDL
DKNASKNYMQ RGDYRGIDDE LDNAYGPLEG YSGIDDELEG AYGPVEGHPN LYSSAALMEE
SEEPLAQEEH PNFGFFAQGS PHVSTETLYW LEDYDDEDND YSVIYYVESM ESSEEDTDTE
QADEDTLESS YEPRAHLWSE GS
//
