ID W5KMD5_ASTMX Unreviewed; 602 AA.
AC W5KMD5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like {ECO:0000313|Ensembl:ENSAMXP00000008747.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000008747.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000008747.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; W5KMD5; -.
DR STRING; 7994.ENSAMXP00000008747; -.
DR Ensembl; ENSAMXT00000008747.2; ENSAMXP00000008747.2; ENSAMXG00000008513.2.
DR eggNOG; KOG4458; Eukaryota.
DR eggNOG; KOG4815; Eukaryota.
DR GeneTree; ENSGT00940000164999; -.
DR HOGENOM; CLU_040178_0_0_1; -.
DR InParanoid; W5KMD5; -.
DR OrthoDB; 2917768at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000008513; Expressed in liver and 11 other cell types or tissues.
DR CDD; cd01270; PTB_CAPON-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR11232; PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER; 1.
DR PANTHER; PTHR11232:SF69; PID DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 29..173
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 173..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 602 AA; 66135 MW; 6BB4BDCBA188DFCF CRC64;
MPGRNRYNLV DDVADSRVPL HNDEAFQHGL HFQAKYVGSL DVPRPNSRME IVAAMRRIRY
EFKAKNIKKK KVSLVVSVDG VKVILRKKQK RKEWTWDESK MLVMHDPIYR IFYVSHDSQD
LKIFSYIARD GSSNTFRCNV FKSKKKSQAM RIVRTVGQAF EVCHKLSLQH AEQNGDGQLD
SAADGESDKS VDEATNEERQ LPGAEQDEVI EVGTESQSAN VCEQAMNEIL KSLSDLNMVK
PGQTLQDLEG VSLYTLSPSS PCSPSLTPLA THHHLHLLQQ QLLQQQQQAQ VAVAQVQLLK
DQMAAETAAR MEAQARTHQL LLQNRDLLQH IALLVKHVSE LESRVNGTTQ YEESPWKGVS
SRSLSLNLKN RYMPGSGLPK TSTPAGDAQN GPPISHMMDC AESYLNLLKL GGPPTAVANG
KPADAGSEQG SDDARQNSSA LDKRFKQIIP KLDPPPPPLN RKRSNRTFSP GSETNGSSFP
DFTSCTASPT DFFSFSNGGS VSCSVSEDSG VRSDNKSLTS PQPGDDPFED RSSALLSTSS
TCSSLPEDRP LAGTPPHLTT PHSYEHTFPF SSPVNETCLH ISLSEDELLE DGICNAATAL
GS
//
