ID   W5L0D1_ASTMX            Unreviewed;       703 AA.
AC   W5L0D1;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 2.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Sterile alpha motif domain containing 11 {ECO:0000313|Ensembl:ENSAMXP00000013293.2};
GN   Name=SAMD11 {ECO:0000313|Ensembl:ENSAMXP00000013293.2};
OS   Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Characidae; Astyanax.
OX   NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000013293.2, ECO:0000313|Proteomes:UP000018467};
RN   [1] {ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA   Jeffery W., Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX   PubMed=25329095; DOI=10.1038/ncomms6307;
RA   McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA   Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA   Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA   Yoshizawa M., Warren W.C.;
RT   "The cavefish genome reveals candidate genes for eye loss.";
RL   Nat. Commun. 5:5307-5307(2014).
RN   [3] {ECO:0000313|Ensembl:ENSAMXP00000013293.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; W5L0D1; -.
DR   Ensembl; ENSAMXT00000013293.2; ENSAMXP00000013293.2; ENSAMXG00000012918.2.
DR   eggNOG; KOG4333; Eukaryota.
DR   GeneTree; ENSGT00940000160830; -.
DR   HOGENOM; CLU_023292_0_0_1; -.
DR   Proteomes; UP000018467; Unassembled WGS sequence.
DR   Bgee; ENSAMXG00000012918; Expressed in camera-type eye and 13 other cell types or tissues.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR10417; GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN; 1.
DR   PANTHER; PTHR10417:SF12; STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 11 ISOFORM X2; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT   REGION          50..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          225..244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          394..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          645..703
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..73
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        129..143
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        431..445
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        688..703
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   703 AA;  76447 MW;  676BDA48A2075F13 CRC64;
     MSKGILQVHP PICDCPGCRI SSPVNRGRLA EKRTIPLPPT RVPKKELASV FSSDDSEGSE
     RVNGDHADIK QEEDLHYTMM RRSSRDSDLS TIISNLHHTR QHGMPEGQPC SDITLASAHS
     DDILGKKRAY SPNSSSECPS DSKKPRSASP KENSHTPTLE PGIHMTPEEH YRRMMSALNE
     HGSYEEQQQR LYQLASNMGV PTHELLRVRQ EALNAVRNPA AMEAHLPSAG SSSSQRRKQG
     LPQHRDAHFT EREMSHPPPL LSPQNAPHIA LGPHLRPPFL GMPSALCQTP AYGFLQPAQA
     EMFARQQEML RKQNLARLEM SAELLRQKEL ENLHRQRLLT DPLGLHPGLP AEHPALRSLQ
     DIPEGHPLRE EINRRNAMLV LRHNNTPLLS LNHQGAAAST SFKESSSRKS SRKGGPLQGD
     QGGGLSEVKE SQGEMRTRDG EVEGQDEDMK DSDSDTEAGD DRPEATSKAD GHGLNSEACQ
     GKDGGKHGEG LKELGEGSGR LSVPCSSAGP DSPSHHLFTP GLSKSEAKYL PPGALPPLPT
     LPGQALPFGF PYTNPYFHTG AMGGLFVDGD EAAAVAAEDI SKWSVEEVFR EQAIDGETLP
     LLTEEHLLNN MGLKLGPALK IRSQVARRIG RIFYMTSFPL ALPLPPSALR PPDRDPLPAE
     TRPPSAGSTS SPFSAPPACR ASPKQENGNP PPAGSYDSTK ALS
//