ID W5L5T3_ASTMX Unreviewed; 272 AA.
AC W5L5T3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Syntaxin binding protein 6 {ECO:0000313|Ensembl:ENSAMXP00000015195.2};
GN Name=STXBP6 {ECO:0000313|Ensembl:ENSAMXP00000015195.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000015195.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000015195.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5L5T3; -.
DR STRING; 7994.ENSAMXP00000015195; -.
DR Ensembl; ENSAMXT00000015195.2; ENSAMXP00000015195.2; ENSAMXG00000014763.2.
DR eggNOG; KOG1983; Eukaryota.
DR GeneTree; ENSGT00940000156499; -.
DR HOGENOM; CLU_101413_0_0_1; -.
DR InParanoid; W5L5T3; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000014763; Expressed in brain and 14 other cell types or tissues.
DR GO; GO:0035542; P:regulation of SNARE complex assembly; IEA:InterPro.
DR CDD; cd15892; R-SNARE_STXBP6; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR InterPro; IPR028258; Sec3-PIP2_bind.
DR InterPro; IPR037822; STXBP6_SNARE.
DR InterPro; IPR042855; V_SNARE_CC.
DR SMART; SM01313; Sec3-PIP2_bind; 1.
DR SUPFAM; SSF58038; SNARE fusion complex; 1.
DR PROSITE; PS50892; V_SNARE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU00290};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 213..272
FT /note="V-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50892"
SQ SEQUENCE 272 AA; 30108 MW; EAF9ACF6FDBD253A CRC64;
ADAGGCAGEE ENKEEDSFLG YWWPGRLHHL HLSVGDQQEA EPGVHHESEA VSGLLFLCQE
ITVDPRPAEA GERHRPQQGE SLDHCRSLWT GCSSVKRRNR LLGHSSCVLT CLSELVKHLF
TPTVLSVERR SSTLRQNGSL SLSFSLCCSF ALSVMLQDCP EFDLTFENAF DQWMAGSSGD
KCMFIQVLHN TCQRYSADRK PEFVNCQSKL LGGNSILHSA ADSVTSAVQK ASQALNERGE
RLGRVEEKTG DMMNSAHQFA DTAHKLAMKH KC
//
