ID W5L863_ASTMX Unreviewed; 940 AA.
AC W5L863;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Uncharacterized LOC103024880 {ECO:0000313|Ensembl:ENSAMXP00000016025.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000016025.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000016025.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5L863; -.
DR Ensembl; ENSAMXT00000016025.2; ENSAMXP00000016025.2; ENSAMXG00000015578.2.
DR eggNOG; ENOG502QR6P; Eukaryota.
DR GeneTree; ENSGT00940000175812; -.
DR HOGENOM; CLU_475609_0_0_1; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000015578; Expressed in intestine and 14 other cell types or tissues.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.160.20; -; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR027897; DUF4559.
DR PANTHER; PTHR35083:SF2; CHROMOSOME 17 CXORF38 HOMOLOG; 1.
DR PANTHER; PTHR35083; RGD1565685 PROTEIN; 1.
DR Pfam; PF15112; DUF4559; 2.
DR SMART; SM00358; DSRM; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR PROSITE; PS50137; DS_RBD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 569..588
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT COILED 211..265
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 940 AA; 107322 MW; 4044B40C0CB9511E CRC64;
MDNCARFRDE KYKNWLKAAE SLYILRNSIR DFVENETETL HKTLRKKLNS DICNEQCDYK
RCQSPLCDTC KRWKSEILET HTGKGKGVYW INCRPYLWPK EKWEVAKVYM PRGHTDHCSF
EQFDISAILN FMGSCTHFEP FVQSKDLNKV TNMRNIVMHS PEFRLDEEKM KNVVENVLSL
ATLLNSHVPG DLYKTVLEAI EKVNMGILAV QEELQGMRNF LEQNKDLLEN LKPQVERLNE
IQEKVDEHEV KIVHLSGRVD DLEKATTTDS MFTIETLQYK NHLIEQTRKR KWPDPVFTEE
IEPSGYRGRV EVNGHTFIGF QVCKKKVMAH QEVAKIALDS LRSEFESTVE PLSSATTTSS
TVVLIQIMLI TLVANSSHLD YCSVLAHLNK CGVKPPQELL LQKGDQFFCE LQLKESFTFN
DEDGSSTKKK TEQQAASIAL QRLSTFLNSS SLAVRNENYK GFLKERLDAL GMDSTKTVYT
IDEEKATEDP EGPGTSIDAS QSEFDFYICS MLFYGTVIVV LEKEISSDSF LTKEEAIESA
YKKFTCVFGL NYPNGGIFPC YAIVIFGFSN KKKAEQQAAK LALQQLSPFL TCSPLAAQNE
NYKGFLKERL EACGIDSTKT EIMQVHMNSL CMLSNKRLRR SFFNNSVSCD LCMCVYICSR
FTEIHSLLTV HHLKPPSVIV ERFTTDQNVS LTLNIALDKF TFKNLSEYTS KKEATRKTYC
LLGFALGIFP KDTDENKATM LVKQDFSKKT LALPKEIVDG EKTSFWCSIG EITYTLTYEG
QGSTEDEAKQ DTLNKALLTL PSLFGFPHLP KSSSTGETED QINSLLRKAG QKDLTFSDER
NQHKVSVTLA FSDYTMTSKM QRTKKENRNL LSNVLWMTKW GLQQPVFTDT EEALGCKAVF
SVQLSCSHPD WEDKLEAAKM KLVQELHRRF RNLVDSGKQD
//
