ID W5L9Q4_ASTMX Unreviewed; 229 AA.
AC W5L9Q4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=MICOS complex subunit mic25a {ECO:0000313|Ensembl:ENSAMXP00000016566.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000016566.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000016566.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5L9Q4; -.
DR Ensembl; ENSAMXT00000016566.2; ENSAMXP00000016566.2; ENSAMXG00000016082.2.
DR GeneTree; ENSGT00390000000903; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000016082; Expressed in heart and 14 other cell types or tissues.
DR GO; GO:0061617; C:MICOS complex; IEA:InterPro.
DR InterPro; IPR007964; MIC19/MIC25.
DR PANTHER; PTHR21588; COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6; 1.
DR PANTHER; PTHR21588:SF17; MICOS COMPLEX SUBUNIT MIC25 ISOFORM X1-RELATED; 1.
DR Pfam; PF05300; MIC19_MIC25; 1.
DR PROSITE; PS51808; CHCH; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT REGION 26..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 229 AA; 26156 MW; 4ACEA5F8E23B89CA CRC64;
MGGRESTTRK VSYGLDQEEK VTVLQGVKLS DDVLQRMRES GSQSSEKSPP PKPGSQKTDP
GPTRPSPAEM QEELRKRFER EQALVREELA RMARREKEAG ADDLKPAVLR ERARTREELE
KAQNLAKQLA RKDAELKHLA AFYKEQLQLM EKKNMDYYQQ TSEMYNEAAT KAEGSIKARN
TLPICPELQS QVLNCYKENR HQTLHCSSLA KEYMNCINSA KKNTMVNHG
//
