ID W5LFZ3_ASTMX Unreviewed; 1787 AA.
AC W5LFZ3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=AT rich interactive domain 1B (SWI1-like) {ECO:0000313|Ensembl:ENSAMXP00000018755.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000018755.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000018755.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR STRING; 7994.ENSAMXP00000018755; -.
DR Ensembl; ENSAMXT00000018755.2; ENSAMXP00000018755.2; ENSAMXG00000018182.2.
DR eggNOG; KOG2510; Eukaryota.
DR GeneTree; ENSGT00940000155634; -.
DR HOGENOM; CLU_000974_1_0_1; -.
DR InParanoid; W5LFZ3; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000018182; Expressed in mesonephros and 14 other cell types or tissues.
DR GO; GO:0035060; C:brahma complex; IEA:InterPro.
DR GO; GO:0016514; C:SWI/SNF complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR021906; BAF250/Osa.
DR InterPro; IPR033388; BAF250_C.
DR PANTHER; PTHR12656:SF11; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1B; 1.
DR PANTHER; PTHR12656; BRG-1 ASSOCIATED FACTOR 250 BAF250; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF12031; BAF250_C; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR PROSITE; PS51011; ARID; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 604..695
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 957..1092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1233..1323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1374..1402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..152
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..459
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..527
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..748
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..780
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 971..985
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1021..1053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1284..1311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1787 AA; 192097 MW; BDF8204D4EF7E827 CRC64;
MGLSKDLSSQ YSSTASHGWG GQQRNHPAMS PGNNGQGGNR SQVSPMDAMS MKRSQLYGMD
NSPYSQQQQQ QQQQTGGGYS TQPYGSPAPH RYPMGMQGRG QVGMAGMQYS QQQVPAQYGQ
QGMGGYCQQG QPPYFSPPQQ QPAAPSQPHY MQPRAPPQQD APQEGYGNRG QPAITPGKPN
HDEMGLNQQD RPSSLPDLSG SIDDLPTGTE AGLSSAVSAS GSTSSQGDQS NPAQSPFSPH
ASPRLSSLRS GPSPSPVGSP VGSSQSRSGP ISPASVPSTQ MAPQTPGNVS DVGSHSTLSQ
SPMSQERGFA SNLQRTGPGS QFGPQQPGPA MSPHPSPGGS MHHSVGSYQQ GGATYGPQSG
QYGPSGNYPR PANYGGAPGP SYSGPGPGMS LGMNASSPMH GQGPGQPCGS MPAGRGPGQP
ASGRPYPAGS SSVAPTSPNM PQSAGPGMGP PPPTVTRKPH ETGPAPCPQN PLASVQARSG
GYSGGPSMGG MGPGGLYNQP PGSNSNRMSL QGPAYNAMPS GENSERHCTS NCLILSDSYS
AQCVSQPPTP SPLSPSPASL SSNHGDDSDS ISSPAWPKTP TSPKLSSATM TNEKIARLYE
MGTEPERRTW VDRYLAFMEE RGTPVPNLPA VGKKPLDLCR LYMCVREIGG LAMVNKNKKW
RELSTVLNVG TSSSSASSLK KQYIQYLFAY ECKVERGEEP PPDAFAMGDS KKQQHQAKVQ
PPSPANSGSL QGPQTPQSTG SSSMTEMPGD LKPPTPATTP HSQMTPQPSG RSSGVSVQDP
FSESCDPAFQ KRGNVPPGVM YQQSANVGDP SVRMQYDANK EPYGGPRKGG SDPYMPGQMP
SSGIQDMYPR GPSGGQGMGP RAQYPYSPNF ERRHGHDGYG QQYPQGMPYS AHGMYPQPQG
YKRPGEAMYG PSAKRHEGEG FGMQYSGQQP DMYGQYGSAY PDRRPMQGQF PYQYNRERMQ
HGGQGPPQHG MMSGGPSSTP SGAPQGWHPR TEMGFPYTSR QGHGPPYSSM NRADDPDGRA
NQDSQWPSHP GQRQSPFPSQ SSSSSLPPMT NRQPPASYQS PPSMPNHIAR APSPAPFSRP
MGGSMSPNKV HLMPSMKMPK TGMPGSMPCS QSGGVPVQGL PPIQREITFP LGSVEATQPQ
LKPRKRLTSK DIGTPEAWRV MMSLKSGLLA ESTWALDTIN ILLYDDNTVS SFTLSQLPGF
LELIVEYFRR CLIEIFGILK EYEVGTEGQK TLLGPIQEPT AKKEESESEL KELDSHSDPE
QPEKKPETAS QRPVPSSTSG ADASEKKKPA ETIDQKGEKD MNARKEKCPS LEPTAKQASK
YDRLPIKVEE REAIDDMVED RSEQLGLVGD FISGLLHWKA GGGDSTAHIQ THLERKYQER
ESQASPVKEF EWENEQGLDS EDCSRVEEEP LKEAQGSTDK NLSAAVVNDV SCFAPPTLPE
NEAKGFSLRN QENSIPLLED EPRCWDEAPL STAEDWQDEL AKRCICISNI VRSLSFVPSN
DADMARHPGL VLILGRLVML HHEHPKRKRT SPTYQREEER GLACSKDEWW WDCLCALHEN
TLVTLANISG QLDLSIYPES ICLPILDGLL HWMVCPSAEA QDPFCTAGGF SSLTPQRLVL
ECLCKLSIQD CNVDLLLATP PLSRQDRLYA TLVRHVGERK SQVCREMAVA VLSNLAQGDS
TAARSIALQK GSIGTVIGFL EDSIAMAQYQ QSPHSLLHAG HPTHPEPPSI NMMCRAAKAL
LAMAQVEENR PEFVLYESRL LDITLSSVLN SSVVAVMCEV LFKLGRS
//
