ID W5LMM2_ASTMX Unreviewed; 582 AA.
AC W5LMM2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=ASPSCR1 tether for SLC2A4, UBX domain containing {ECO:0000313|Ensembl:ENSAMXP00000021084.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000021084.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000021084.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5LMM2; -.
DR STRING; 7994.ENSAMXP00000021084; -.
DR Ensembl; ENSAMXT00000021084.2; ENSAMXP00000021084.2; ENSAMXG00000020425.2.
DR eggNOG; KOG2699; Eukaryota.
DR GeneTree; ENSGT00940000156853; -.
DR HOGENOM; CLU_025227_0_0_1; -.
DR InParanoid; W5LMM2; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000020425; Expressed in testis and 14 other cell types or tissues.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd16105; Ubl_ASPSCR1_like; 1.
DR CDD; cd17075; UBX1_UBXN9; 1.
DR InterPro; IPR003116; RBD_dom.
DR InterPro; IPR021569; TUG-UBL1.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46467; TETHER CONTAINING UBX DOMAIN FOR GLUT4; 1.
DR PANTHER; PTHR46467:SF1; TETHER CONTAINING UBX DOMAIN FOR GLUT4; 1.
DR Pfam; PF11470; TUG-UBL1; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50898; RBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 6..75
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT REGION 147..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..224
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 63339 MW; 4E5BB8E41DC23F9B CRC64;
MAASSTAVSV LSPNGRRQTV KVSPNTPLLQ VLEEVCKKQG FNPDDHGLKF QRNVLDLTLQ
WRFASLPNNA KLEVVPSTRQ RGGTESTVRI ALQLEDGSRL QGSFSSGQTL WELLKHFPQT
RITDLDAAGP TPVCVYMRDE VECLDLSRPS SPTQYVVKTS NTLGNGEPME NAATPTDTIA
TATASQPTPE HLEAPSGAST AVNPPLPDRP DEPTPAPVPM ETPSPPLQSS EAAVAHTSQT
LPVQKEEADP SQDQHQAVRP KIRQVDNKGH QDSKAELQMD DEQPGPSHAK LPPHSNFVPF
SGGGQRLGGS GGLPPSSSSS SSSSPVFSGP PKAKKSKPSH EVKSSASAKF GAKDSEEREE
YLEPVHREPL IYHLDTARRT SAEEDLTDEF FEVTVDDVRK RFSQLKSERY VLLEEAPLMT
QALREAQMKE KMDRYPKVVL RVQFPDRQVL QGFFRPQETV LLCVLLFPVI APPKTVLNDP
NATLFQANLF PAALVYFGSD AKTGLLTATS ISVRLFHLLC IPRSPAPTSC SQPPQDSVPL
EPSKPSSIQP GPEDTSDPES QAVKPARTDP AKVPKWLKLP GV
//
