ID W5LN55_ASTMX Unreviewed; 417 AA.
AC W5LN55;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=ethanolamine kinase {ECO:0000256|ARBA:ARBA00038874};
DE EC=2.7.1.82 {ECO:0000256|ARBA:ARBA00038874};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000021267.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000021267.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
CC {ECO:0000256|ARBA:ARBA00037883}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR AlphaFoldDB; W5LN55; -.
DR STRING; 7994.ENSAMXP00000021267; -.
DR Ensembl; ENSAMXT00000021267.2; ENSAMXP00000021267.2; ENSAMXG00000020644.2.
DR eggNOG; KOG2686; Eukaryota.
DR GeneTree; ENSGT00950000182939; -.
DR HOGENOM; CLU_012712_2_1_1; -.
DR InParanoid; W5LN55; -.
DR OrthoDB; 144299at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000020644; Expressed in pharyngeal gill and 14 other cell types or tissues.
DR CDD; cd05156; ChoK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603:SF103; CHOLINE KINASE ALPHA ISOFORM X1; 1.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
SQ SEQUENCE 417 AA; 48584 MW; FD6C4508FB418E67 CRC64;
MKTKFINGVS SSPSMSLGLL VTENALQVQP DTEPDCKDIR PDEPDQQTKH KAFMWCREFL
HGAWKTVEEN DFQITVIRGG LSNKLFLCAL PEEQQSVGDE PRNVLLRLYG AILQMSCNKG
ESRQSNKDNH FQGAEAMILE SVMFAILAER QLGPKLYGIF PQGRLEQFVP SRKLNTDELK
IPSISSEIAE KIAKFHRMRM PFNKEPKWLF GTMEKYMSQV QSLAFTRETH LRKFSRLMSY
NLRQEMESLR CLLESTQSPV VFCHNDLQEG NILLLSGREN MDKQKLMLID FEYSSYNYRG
FDIGNFFCEW TYDYTCDVSP YFKTTTKNYP TKAQQMHFFK SYLLEYDPGI ANLGEEDQLK
LREDMLVEVN RFALASHFFW GLWSIIQARI STIEFGYLDY AMARFDSYFE LKKELGI
//
