ID W5LNR3_ASTMX Unreviewed; 454 AA.
AC W5LNR3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Si:ch211-166g5.4 {ECO:0000313|Ensembl:ENSAMXP00000021475.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000021475.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000021475.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; W5LNR3; -.
DR Ensembl; ENSAMXT00000021475.2; ENSAMXP00000021475.2; ENSAMXG00000020861.2.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000158525; -.
DR HOGENOM; CLU_042232_2_1_1; -.
DR InParanoid; W5LNR3; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000020861; Expressed in camera-type eye and 14 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 6.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24390:SF197; GH18834P-RELATED; 1.
DR PANTHER; PTHR24390; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR Pfam; PF13894; zf-C2H2_4; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 5.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 67..94
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 191..218
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 219..246
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 249..276
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 277..305
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 30..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 49565 MW; 8070A94711E6517C CRC64;
MDASWSNFLF QTTGAQTQVD GSLQAELMPQ SPAPEHMAPP PSTVDTAALN EDPEPVKPPP
RPARVAHICA ICSKQFKNSY NLRRHQSVHT GIRMKSGSSQ NQEGGAKEVV ERPTVPLSLL
QLTMPEPQAP SLTPQDMLPT QMPQQPLVAQ DTNESVMVSV ASTVTALPPA AIVVMATPEP
VQNPNPVRKN HACETCGKAF RDVYHLNRHR LSHSDEKPFS CPICQQRFKR KDRMSHHVRS
HQGGVEKPYI CPHCSKAFSP DHLNSHVRQV HSSERPFKCP QTCESSFATK DRLRAHMIRH
EEKVPCHICG KLLSAAYITD HMRVHNQSQH HACHLCNRFT TLTYLRIHAQ KHHGQEWKES
SGGFGSAGAG GVLVCQLCGV HCKTPTQLQG HMGTHNPPMN DPAPVSSSSD GVASAAGTVT
LSSMTSAPTV FVSGNAVVDL LVTDCSCIAQ QPQS
//
