ID W5LTM2_ASTMX Unreviewed; 505 AA.
AC W5LTM2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Kelch repeat and BTB domain containing 13 {ECO:0000313|Ensembl:ENSAMXP00000026486.2};
GN Name=KBTBD13 {ECO:0000313|Ensembl:ENSAMXP00000026486.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000026486.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000026486.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5LTM2; -.
DR STRING; 7994.ENSAMXP00000026486; -.
DR Ensembl; ENSAMXT00000026507.2; ENSAMXP00000026486.2; ENSAMXG00000025781.2.
DR eggNOG; KOG1072; Eukaryota.
DR GeneTree; ENSGT00940000161629; -.
DR HOGENOM; CLU_049036_0_0_1; -.
DR InParanoid; W5LTM2; -.
DR OrthoDB; 3932725at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR GO; GO:0030018; C:Z disc; IEA:Ensembl.
DR CDD; cd18486; BACK_KBTBD13; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46375; KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED; 1.
DR PANTHER; PTHR46375:SF5; KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 2.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 2.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 33..100
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 505 AA; 56841 MW; ECFFDBB21ABB5C08 CRC64;
MKITGSNLME PSSCAGSEDG AVKVCQALVL ENSAVRVRID GSIFTVDRML LESNCEYFRA
LFQSGMKECQ QEEIHLQVVS ACGFLVALQV IQGERPILSD DETFEAIECA AFLQVQPLVR
HLVNLVNSDN CLLMYHTAAT YGVLELFKSA ALFIRDMYKD LKEEVKCLPK ELTDYVESLV
PSTYVMVGTH SPSNKSLQNN MRTVCYLDED EKDWKVLTHL PLDASTTMAG VTVLNNKIYI
VGGLYDLSNK VVDSGFCYDV ASSIWSTFSS PQQLRYNCTL VGHDGSLYAL GGEYNRTAIS
SVERYNVSTD TWSFAAHLPR PASAVPCTKS MGRIFTCLWK PKDATEIYEY LPVTNQWVLL
TTLVRHQSYG HCMVAHRDNL YVMRNGPCDD FLRCMMDCYN LTTCQWTAMA GQYENSKGAL
FTSVVRGDSV FTVNRRATVE YSIEDNKWRT KKEMTGFPRI GSMWTFLLRL PKKSTEPLGK
PELTNGQHFE VLSDLPSRSS VECYD
//
