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Database: UniProt
Entry: W5LXP8_LEPOC
LinkDB: W5LXP8_LEPOC
Original site: W5LXP8_LEPOC 
ID   W5LXP8_LEPOC            Unreviewed;       649 AA.
AC   W5LXP8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   16-JAN-2019, entry version 31.
DE   RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE            EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
OS   Lepisosteus oculatus (Spotted gar).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC   Lepisosteus.
OX   NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000000905, ECO:0000313|Proteomes:UP000018468};
RN   [1] {ECO:0000313|Ensembl:ENSLOCP00000000905, ECO:0000313|Proteomes:UP000018468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT   "The Draft Genome of Lepisosteus oculatus.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLOCP00000000905}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose
CC         residues in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|RuleBase:RU000675};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|RuleBase:RU003679, ECO:0000256|SAAS:SAAS00534244}.
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DR   EMBL; AHAT01012339; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_006635641.2; XM_006635578.2.
DR   RefSeq; XP_015212414.1; XM_015356928.1.
DR   Ensembl; ENSLOCT00000000909; ENSLOCP00000000905; ENSLOCG00000000812.
DR   GeneID; 102691690; -.
DR   CTD; 2720; -.
DR   GeneTree; ENSGT00390000006586; -.
DR   OMA; GWGKGIV; -.
DR   OrthoDB; 179316at2759; -.
DR   Proteomes; UP000018468; Linkage group LG11.
DR   GO; GO:0005773; C:vacuole; IBA:GO_Central.
DR   GO; GO:0004565; F:beta-galactosidase activity; IBA:GO_Central.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; -; 2.
DR   InterPro; IPR026283; B-gal_1-like.
DR   InterPro; IPR025300; BetaGal_jelly_roll_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR019801; Glyco_hydro_35_CS.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421; PTHR23421; 1.
DR   Pfam; PF13364; BetaGal_dom4_5; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PIRSF; PIRSF006336; B-gal; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000018468};
KW   Glycosidase {ECO:0000256|RuleBase:RU000675,
KW   ECO:0000256|SAAS:SAAS00108888};
KW   Hydrolase {ECO:0000256|RuleBase:RU000675,
KW   ECO:0000256|SAAS:SAAS00108869};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     15       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        16    649       Beta-galactosidase. {ECO:0000256|SAM:
FT                                SignalP}.
FT                                /FTId=PRO_5013107901.
FT   DOMAIN       35    349       Glyco_hydro_35. {ECO:0000259|Pfam:
FT                                PF01301}.
FT   DOMAIN      538    607       BetaGal_dom4_5. {ECO:0000259|Pfam:
FT                                PF13364}.
FT   ACT_SITE    182    182       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR006336-1}.
FT   ACT_SITE    262    262       Nucleophile. {ECO:0000256|PIRSR:
FT                                PIRSR006336-1}.
SQ   SEQUENCE   649 AA;  72455 MW;  D5A7536AF2649CE6 CRC64;
     MAFIWVFLLL PTITGVKLAC AAPRSFEIDY ENDCFLKDGE PFRYISGSIH YSRIPRVYWK
     DRLIKMYMAG LNAIQTYVPW NYHEPLPQQH NFTGDRDLEH FLKLANDLGL LVVLRPGPYI
     CAEWEMGGLP AWLLKKKDIV LRSSDPDYIT AVDQWMGKLL PMIKPFLYQN GGPIITVQVE
     NEYGSYFACD YNYLRHLTKL FRSHLGEEVV LFTTDGAGLG FLKCGALQGL YATVDFGPGG
     NVTAAFSAQR HAEPKGPLVN SEFYTGWLDH WGQHHSVVNK NTVAKSLNEI LAAGANVNLY
     MFIGGTNFGY WNGANTPYAP QPTSYDYDAP LTEAGDLTDK YFAIRDVIRL YRKIPDGPVP
     PTTPKFSYGA VKMNKLQTVT DALDSLSFSG PVKSVYPITF IEMNQHFGFI LYQTKIPKDC
     SEPTPLSSLL NGVHDRAYIT VNGFPKGILE RDKSLTINIT GKAGDLLDIL VENMGRVNYG
     KYINDFKGLV SNLTLGNDTL SNWLIYSLSI DEAVSQGVLW ERSQERAFQP PSDLTAPAFY
     GGSFSIPSGV PDLPQDTYIQ FPGWRKGQVW INGFNLGRYW PARGPQVTLY VPASVLSTAA
     PNNITVLELE SSPCDFGPCT VDFTEAPVLN ATVEHPALKR KLFIKEDLA
//
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