ID W5LYH2_LEPOC Unreviewed; 232 AA.
AC W5LYH2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=palmitoyl-protein hydrolase {ECO:0000256|ARBA:ARBA00012423};
DE EC=3.1.2.22 {ECO:0000256|ARBA:ARBA00012423};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000001179.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000001179.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 2
CC family. {ECO:0000256|ARBA:ARBA00006499}.
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DR EMBL; AHAT01009310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006631266.1; XM_006631203.2.
DR RefSeq; XP_015203860.1; XM_015348374.1.
DR RefSeq; XP_015203861.1; XM_015348375.1.
DR RefSeq; XP_015203862.1; XM_015348376.1.
DR AlphaFoldDB; W5LYH2; -.
DR STRING; 7918.ENSLOCP00000001179; -.
DR MEROPS; S09.025; -.
DR Ensembl; ENSLOCT00000001183.1; ENSLOCP00000001179.1; ENSLOCG00000001047.1.
DR GeneID; 102694545; -.
DR KEGG; loc:102694545; -.
DR CTD; 11313; -.
DR eggNOG; KOG2112; Eukaryota.
DR GeneTree; ENSGT00940000156197; -.
DR HOGENOM; CLU_049413_3_5_1; -.
DR InParanoid; W5LYH2; -.
DR OMA; WYDILAM; -.
DR OrthoDB; 4670340at2759; -.
DR Proteomes; UP000018468; Linkage group LG6.
DR Bgee; ENSLOCG00000001047; Expressed in camera-type eye and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IBA:GO_Central.
DR GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR003140; PLipase/COase/thioEstase.
DR PANTHER; PTHR10655:SF13; ACYL-PROTEIN THIOESTERASE 2; 1.
DR PANTHER; PTHR10655; LYSOPHOSPHOLIPASE-RELATED; 1.
DR Pfam; PF02230; Abhydrolase_2; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 13..228
FT /note="Phospholipase/carboxylesterase/thioesterase"
FT /evidence="ECO:0000259|Pfam:PF02230"
SQ SEQUENCE 232 AA; 25155 MW; 02B96ECE0D65DB75 CRC64;
MCGNNMSVPL LTEAVTVSGT ERETAAVIFL HGLGDTGHGW ADAMTSIRLP YVKYICPHAP
RIPVTLNMKM VMPSWFDLMG LSPESPEDEA GIKKAAENIK ALIDHEVKNG IPAHRVMLGG
FSQGGALSLY TALTCQFKLA GVVALSCWLP LHRSFPQAAS SSANKDTPIL QCHGEMDPMI
PVQFGALTAE KLKSIVSPQK ISFHTFPGLM HSSCPQEMSA VKEFIEKQLP RI
//
