ID W5M0W0_LEPOC Unreviewed; 329 AA.
AC W5M0W0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Mitochondrial calcium uptake 2 {ECO:0000313|Ensembl:ENSLOCP00000002017.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000002017.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000002017.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01003332; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01003333; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5M0W0; -.
DR STRING; 7918.ENSLOCP00000002017; -.
DR Ensembl; ENSLOCT00000002022.1; ENSLOCP00000002017.1; ENSLOCG00000001747.1.
DR eggNOG; KOG2643; Eukaryota.
DR GeneTree; ENSGT00950000183079; -.
DR HOGENOM; CLU_027103_0_0_1; -.
DR InParanoid; W5M0W0; -.
DR OMA; LKYQEFH; -.
DR Proteomes; UP000018468; Linkage group LG3.
DR Bgee; ENSLOCG00000001747; Expressed in intestine and 13 other cell types or tissues.
DR GO; GO:1990246; C:uniplex complex; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR GO; GO:0036444; P:calcium import into the mitochondrion; IBA:GO_Central.
DR GO; GO:0051560; P:mitochondrial calcium ion homeostasis; IBA:GO_Central.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039800; MICU1/2/3.
DR PANTHER; PTHR12294:SF3; CALCIUM UPTAKE PROTEIN 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12294; EF HAND DOMAIN FAMILY A1,A2-RELATED; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 278..313
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 329 AA; 38374 MW; 66465E702FEB1F88 CRC64;
FSPRRLRFDQ FASVLYEGEP YMTPRDFLYS VMLEHVDRKL HKKMLTKEEV HGMLNIASKT
KPSSGLFRNL GDYGLISYTE YLFLLTILTK PHTGFQIAFK MLDVDGNEHV DRREFLKLKN
IISKRKEAKP PKDDAEKSGA EVGDEVYTTL QAYFFGRTGN QKLQYKDFCR FMEDLQAEVQ
EMEFLQFSKG MDTMRREDFA EWLLHYTNEE DNEAYWENMR KRIPPGQSIT FEEFKSFCLF
TNNIEDFAFT VKIINEANRP IGMAEFERAV SIATGHKLSE NVLDTVFKIF DLDGDNCLSH
KEFLGVMKDR IQRGLKVQPQ QAVAACWGC
//
