ID W5M1W7_LEPOC Unreviewed; 1692 AA.
AC W5M1W7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000002375.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000002375.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHAT01035081; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035082; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035083; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035084; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035086; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035087; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035088; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035089; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01035090; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7918.ENSLOCP00000002375; -.
DR Ensembl; ENSLOCT00000002380.1; ENSLOCP00000002375.1; ENSLOCG00000002044.1.
DR eggNOG; ENOG502QQ5W; Eukaryota.
DR GeneTree; ENSGT00950000183145; -.
DR HOGENOM; CLU_235529_0_0_1; -.
DR InParanoid; W5M1W7; -.
DR OMA; EVTCRGS; -.
DR Proteomes; UP000018468; Linkage group LG5.
DR Bgee; ENSLOCG00000002044; Expressed in heart and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 16.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071:SF24; SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130-RELATED; 1.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 16.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 16.
DR SUPFAM; SSF56487; SRCR-like; 16.
DR PROSITE; PS00420; SRCR_1; 4.
DR PROSITE; PS50287; SRCR_2; 16.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 22..125
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 129..227
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 232..326
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 330..428
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 433..533
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 537..635
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 640..741
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 745..843
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 848..945
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 950..1050
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1055..1155
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1164..1262
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1267..1367
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1378..1476
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1481..1584
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1589..1686
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 88..98
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 152..216
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 165..226
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 196..206
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 298..308
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 353..417
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 366..427
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 397..407
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 458..522
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 471..532
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 502..512
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 560..624
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 573..634
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 604..614
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 679..740
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 710..720
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 768..832
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 781..842
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 812..822
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 914..924
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 975..1039
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 988..1049
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1019..1029
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1080..1144
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1093..1154
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1124..1134
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1187..1251
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1200..1261
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1231..1241
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1292..1356
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1305..1366
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1336..1346
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1447..1457
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1553..1563
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1655..1665
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 1692 AA; 182277 MW; 864BB22BE4F3CB5F CRC64;
LLQNICQVLS LISGYTADIN IVRIREQINH CDGRVEVFKN GQWGTVCASS WHDENGKVVC
NQLNCGTYER FYHAPGSSLP IVLNEVQCSG TESSLLDCPE NSLTTFFNFF LTSCSHENDI
RVKCSGDTTR LIGTQSQGRL EVNRRGSWRS VCSQSVDSRD ADVVCRELGC GVSRAVLGGA
SSGQGTGPVW ADEIQCRGDE VKLAYCPVLK REQHNCTHAD DVSIICSGCE DLRLVGFGNR
CDGRVEIFKN GQWGTYCDSD YYYKNGEVVC DQLNCGTFIG AYYSPGKSKP ISLHGVRCSG
TESSLLDCPS DSKSCTHDKD IRVKCSGDTA RLSGGMCYGR LEVNRGGTWG SVCSQSVDSR
DADVVCRELG CGVSRAVLGG ASSGQGTGPV WADEIQCRGD EEKLAHCPVL KREQHNCTHA
DDISIVCYET ERLRLMGGVS NCSGRVEVLY GGSWGTVCDD SWDLRDAQVV CRQLGCGEAV
SAGTEASWGE GNGTVWLDEV TCGGRELHLW DCEHAALGQS NCRHKEDAGV SCARDTARLS
GGMCYGRLEV NRGGTWRSVC SQSVDSTDAD VVCRELGCGV SRAVLGGASS GQGTGPIWAD
EIQCRGDEEK LAYCPVLKRE QHNCTHADDV SIDCSEHGLL RLSGAESPCA GRLEVYHRGS
WGTVCDDSWW DLRDAQVVCR QLGCGEAVSA GTEASWGEGN GTVWLDEVTC RGSELHLWDC
EHAALGQSDC QHRRRAGVRC AGDTARLSGG MCYGRLEVNR GGSWGSVCSQ SVDSRDADVV
CRELGCGVSR AVLGGASSGQ GTGPVWADEI QCRGDEEKLA HCPVLKREQH NCTRADDVSI
VCSEFKQLRL VSEQFECAGR AEVFYNGTWG SICQNRMDPH TASLICRQLN CGDFDKFYTP
DDGSGLKWLD DVQCKKHDVS LWQCPHSPWG ENSCTERDVA GLICKETDRL RLMGGVSNCS
GRVEVLYGGS WGTVCDDSWD LRDAQVVCRQ LGCGEAVSAG TEASWGEGNG TVWLDEVTCR
GSELHLWDCE HAALGQSDCR HKEDAGVSCA KPERIKLSGG PSACSGRVEV LYGGSWGTVC
DDSWDLRDAQ VVCRQLGCGE AVSAGTEASW GEGNGTVWLD EVTCRGSELH LWDCEHAALG
QSDCQHRRRA GVRCAALFML GDTARLSGGT CQGRLEVNRG GSWRSVCSQS VDSRDADVVC
RELGCGVSRA VLGGASPGQG TGPVWGDEIQ CQGDEEKLAY CPVLKREQHN CTHADDVSIV
CYGYTDFRLA SGPDRCSGRV EMKLGAQWGT VCDQVWDLRD ATVLCQQLNC GYAEAVLGPA
RFGQGSGSTW TDVFDCEGTE TELRHCPISP WAHSSCSHSR DVGVVCSGLT LPGAAGGVRL
VGGAGRCDGR VEVFSSGKWG RLLNSSWTDS AASVLCRQLG CGSALETSSS SRYGPGRSDV
CFSGVSCSGN ETHLGNCSRP QPVSCSSASD VGVLCEKTER LRLVGGVSNC SGRVEVLYGG
SWGTVCDDSW DLRDAQVVCR QLGCGEACGN AQFPAPVSFS QGAGPIWLDE VGCLGNESSL
WECPSRPWGQ HDCGHKEDVT IVCSGFKQLR LVSEQFECAG RAEVFYNGTW GSICQNLMDS
HTASLICRQV NCGDFVKFDI PDDGSGLKWL DNVQCKKHDV SLWQCPHSPW GENSCTDRDV
AGLICTGTVF YR
//
