ID W5M2L5_LEPOC Unreviewed; 449 AA.
AC W5M2L5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Ankyrin repeat and SOCS box containing 6 {ECO:0000313|Ensembl:ENSLOCP00000002623.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000002623.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000002623.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; AHAT01021632; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006640653.1; XM_006640590.2.
DR AlphaFoldDB; W5M2L5; -.
DR STRING; 7918.ENSLOCP00000002623; -.
DR Ensembl; ENSLOCT00000002629.1; ENSLOCP00000002623.1; ENSLOCG00000002248.1.
DR GeneID; 102695814; -.
DR KEGG; loc:102695814; -.
DR CTD; 140459; -.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00390000006784; -.
DR HOGENOM; CLU_000134_52_2_1; -.
DR InParanoid; W5M2L5; -.
DR OMA; HLCRVHI; -.
DR OrthoDB; 5352456at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000018468; Linkage group LG21.
DR Bgee; ENSLOCG00000002248; Expressed in muscle tissue and 13 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24180; CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED; 1.
DR PANTHER; PTHR24180:SF43; NAD-DEPENDENT DEACETYLASE SIR2B; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 4.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 100..132
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 134..167
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 168..206
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 378..427
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 449 AA; 49414 MW; A0EBEF25A2A909CB CRC64;
MPFLHGFRRI TYEYQSLVDA VLRVLRLEEG RESRDSDPAP ADGPAPRDAL TALLESEAQS
AVFKEGVSCA LFKVAETGLV SAAEILLQYG ADLNFEDPVN YYNPLHIAVL RNQPRMVELL
AGHGADINKR DRIHESSPLD LASEEGERLS CLRVLLDLGA DVNAKDKNGK TALIHALASS
DGVTVCNTDS IRLLLERGAD VGATTQEGET VLSQLVFLVS EALEGTAEDA AAIGDFCLEA
ARLLLAHGAD PSRCLSHSEE EGAREEEEEE VWAYEPSLTQ VCLEHFDLLY PLAVLLLQSG
AAFHCSRHGA TCWTGYCPTF NRLCEALRQS DRDAASTLLA KAEYLLELAT ASSPAPALPP
GFEVCVSSYV PRAEEVLGLY RRLRERRAAP AALQQLCRAR IRCLLQPWPL ERKVQALPLP
DRLKEYLLPE RKYAPRPGQD SFRPCLTLR
//
