ID W5M3U3_LEPOC Unreviewed; 146 AA.
AC W5M3U3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cystatin-like {ECO:0000313|Ensembl:ENSLOCP00000003051.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000003051.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000003051.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cystatin family.
CC {ECO:0000256|ARBA:ARBA00009403}.
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DR EMBL; AHAT01012642; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006626685.1; XM_006626622.2.
DR AlphaFoldDB; W5M3U3; -.
DR STRING; 7918.ENSLOCP00000003051; -.
DR Ensembl; ENSLOCT00000003057.1; ENSLOCP00000003051.1; ENSLOCG00000002595.1.
DR GeneID; 102685300; -.
DR KEGG; loc:102685300; -.
DR eggNOG; ENOG502SB32; Eukaryota.
DR GeneTree; ENSGT00390000009872; -.
DR HOGENOM; CLU_149427_0_0_1; -.
DR InParanoid; W5M3U3; -.
DR OMA; AQHAVKM; -.
DR OrthoDB; 3950585at2759; -.
DR Proteomes; UP000018468; Linkage group LG2.
DR Bgee; ENSLOCG00000002595; Expressed in bone element and 10 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0031982; C:vesicle; IBA:GO_Central.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IBA:GO_Central.
DR CDD; cd00042; CY; 1.
DR Gene3D; 3.10.450.10; -; 1.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR046350; Cystatin_sf.
DR PANTHER; PTHR46186; CYSTATIN; 1.
DR PANTHER; PTHR46186:SF13; SI:BUSM1-57F23.1; 1.
DR Pfam; PF00031; Cystatin; 1.
DR SMART; SM00043; CY; 1.
DR SUPFAM; SSF54403; Cystatin/monellin; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..146
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018539108"
FT DOMAIN 39..145
FT /note="Cystatin"
FT /evidence="ECO:0000259|SMART:SM00043"
SQ SEQUENCE 146 AA; 16565 MW; FDCD5E11B946504D CRC64;
MAFIKKILLF FSLMPVFVLS ESDQIVEDVI EEIKPRYIKP VGAPFRMDPN SPEIQNVANN
AVAEYNKISR GKNYFILLNV TSAEAQVTNT ITYKLNAEIG RSKCKKSEDI NLKACALGKK
RLNCHFEIQF HPSKNKNALI DSKCKK
//
