ID W5M4D6_LEPOC Unreviewed; 265 AA.
AC W5M4D6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Uroplakin-1b {ECO:0000256|ARBA:ARBA00017701};
DE AltName: Full=Uroplakin Ib {ECO:0000256|ARBA:ARBA00031616};
GN Name=UPK1B {ECO:0000313|Ensembl:ENSLOCP00000003244.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000003244.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000003244.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Heterodimer with uroplakin-3A (UPK3A) or uroplakin-3B (UPK3B).
CC {ECO:0000256|ARBA:ARBA00011304}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AHAT01003268; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006628039.1; XM_006627976.2.
DR AlphaFoldDB; W5M4D6; -.
DR STRING; 7918.ENSLOCP00000003244; -.
DR Ensembl; ENSLOCT00000003251.1; ENSLOCP00000003244.1; ENSLOCG00000002757.1.
DR GeneID; 102692189; -.
DR KEGG; loc:102692189; -.
DR CTD; 7348; -.
DR eggNOG; KOG3882; Eukaryota.
DR GeneTree; ENSGT00940000160779; -.
DR HOGENOM; CLU_088971_1_0_1; -.
DR InParanoid; W5M4D6; -.
DR OMA; AECIYFV; -.
DR OrthoDB; 4150771at2759; -.
DR Proteomes; UP000018468; Linkage group LG3.
DR Bgee; ENSLOCG00000002757; Expressed in pharyngeal gill and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03156; uroplakin_I_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR47110; TESTIS-SPECIFIC EXPRESSED PROTEIN 55; 1.
DR PANTHER; PTHR47110:SF2; UROPLAKIN-1B; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR SUPFAM; SSF48652; Tetraspanin; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 265 AA; 30139 MW; 1AB9AA1845A308C7 CRC64;
MVAKSDIGVR CFQAFLAWGN FVIACCGLAL MAMCIFFIFD RDHLYVLVYA TGNDSIWRAA
WIGLFTGFAL FCTAVFGMYA VLKSKRGLLL VYILLMIFIF AFEVASAITA ATHKDWFVPN
LFLKQMLENY NKPLPQNLPS TQDEIYKNSG ITSTWNMIMT EYQCCGVYGP QDWLQYNSQF
RQQNSDSEYP WPRQCCLQDG TGGIVNVNAC KIGVEPYLFT QGCYDYIAGP LIRQGLGVSW
FGFAILCWTF FVVIGVMFYY TQLDS
//
