ID W5M6B1_LEPOC Unreviewed; 217 AA.
AC W5M6B1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Complement C8 gamma chain {ECO:0000313|Ensembl:ENSLOCP00000003919.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000003919.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000003919.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; AHAT01003229; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5M6B1; -.
DR STRING; 7918.ENSLOCP00000003919; -.
DR Ensembl; ENSLOCT00000003927.1; ENSLOCP00000003919.1; ENSLOCG00000003306.1.
DR eggNOG; ENOG502S0KX; Eukaryota.
DR GeneTree; ENSGT00440000034309; -.
DR InParanoid; W5M6B1; -.
DR OMA; LMCVCLW; -.
DR Proteomes; UP000018468; Linkage group LG3.
DR Bgee; ENSLOCG00000003306; Expressed in liver and 8 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005579; C:membrane attack complex; IEA:InterPro.
DR GO; GO:0006956; P:complement activation; IEA:InterPro.
DR Gene3D; 2.40.128.20; -; 1.
DR InterPro; IPR002968; A1-microglobln.
DR InterPro; IPR043245; C8G.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR PANTHER; PTHR47304; COMPLEMENT COMPONENT C8 GAMMA CHAIN; 1.
DR PANTHER; PTHR47304:SF1; COMPLEMENT COMPONENT C8 GAMMA CHAIN; 1.
DR Pfam; PF00061; Lipocalin; 1.
DR PRINTS; PR01215; A1MCGLOBULIN.
DR PRINTS; PR00179; LIPOCALIN.
DR SUPFAM; SSF50814; Lipocalins; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..217
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004865705"
FT DOMAIN 54..198
FT /note="Lipocalin/cytosolic fatty-acid binding"
FT /evidence="ECO:0000259|Pfam:PF00061"
SQ SEQUENCE 217 AA; 24306 MW; 6BF7A0FE26FFE25C CRC64;
MAGVRAACCV FVLAVWALCL PDTGGAARPS RRRQQESPID KIAVQEDFNL DQMSGKWFLI
GVASECESLR QSNAVLEGTT ITLKVPPKSP QTSAKSLLSV STLRKLDLQC WDIRQEYHLT
PTKGRFLLKG PGTSNNIDIV VAKTDYRGYA ILYYQKRGKI TIKLYGRSTE IPEDILNMYE
DLAQDQKISI DSVYYFPKYG FCESADEFHI LPEAPTA
//
