ID W5M6R0_LEPOC Unreviewed; 184 AA.
AC W5M6R0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 {ECO:0000313|Ensembl:ENSLOCP00000004068.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000004068.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000004068.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01035904; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5M6R0; -.
DR STRING; 7918.ENSLOCP00000004068; -.
DR Ensembl; ENSLOCT00000004076.1; ENSLOCP00000004068.1; ENSLOCG00000003439.1.
DR eggNOG; KOG1430; Eukaryota.
DR GeneTree; ENSGT00940000160236; -.
DR HOGENOM; CLU_007383_6_3_1; -.
DR InParanoid; W5M6R0; -.
DR OMA; WEESRCR; -.
DR Proteomes; UP000018468; Linkage group LG5.
DR Bgee; ENSLOCG00000003439; Expressed in liver and 13 other cell types or tissues.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 5..107
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 184 AA; 21420 MW; 7A3E06A3C3A354D9 CRC64;
QISGEKVLYT CALRPTGIYG ENHQVMKDFY KRGMKTGSWI LRAITNNIEQ GRVYAGNVAW
MHLLACRSLQ ERPLLLGGQV YFCYDESPYK SFVDFNMQFL SGFGFREVRI PMWLLWAAAM
TNDLLHTLLR PLCNYSPQLN RYTLAVASTT FTVSTDKARR HFGYQPLYSW EESRCRTLAW
VQTF
//
