ID W5M7D3_LEPOC Unreviewed; 743 AA.
AC W5M7D3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Neural cell adhesion molecule 3 {ECO:0008006|Google:ProtNLM};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000004291.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000004291.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AHAT01019112; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01019113; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5M7D3; -.
DR STRING; 7918.ENSLOCP00000004291; -.
DR Ensembl; ENSLOCT00000004299.1; ENSLOCP00000004291.1; ENSLOCG00000003618.1.
DR eggNOG; KOG3510; Eukaryota.
DR GeneTree; ENSGT00940000155743; -.
DR HOGENOM; CLU_010961_3_0_1; -.
DR InParanoid; W5M7D3; -.
DR OMA; SATFMLH; -.
DR Proteomes; UP000018468; Linkage group LG24.
DR Bgee; ENSLOCG00000003618; Expressed in larva and 9 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR009138; Neural_cell_adh.
DR PANTHER; PTHR12231; CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR12231:SF253; NEURAL CELL ADHESION MOLECULE; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR PRINTS; PR01838; NCAMFAMILY.
DR SMART; SM00060; FN3; 2.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 687..708
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..112
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 117..204
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 213..301
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 304..473
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 475..577
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 579..679
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 216..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 743 AA; 80739 MW; 59A35902FB610631 CRC64;
FLEGRSCCFS LSFLCAGLGK SLEIVSNSGD VELENSHFMV CKVSARGGEG TITWHKDEEE
IEDGQDNFVI TKIDEVSSKL TIKNARREDG GTYICSCEFE DGIVKTAKQT ITIIMKPKIL
TTTSYYEFLA GKDATMPCEV TGIPMPTVTW KFKDRGVIDS TSGRISILPG NSLQIQNISR
VDHGTYVCEA WIKAKERNEV AKLSVSVVVN APPHMRTHEQ EKSVAAGPAS NVSLTCPVSG
HPPPSISWAS PERSDQSRYQ FNSDHSELII HSVSKNDEGV YNCTATNAFG TYSSRIVLGV
SVRPDVQQLG TREAQPGETV SVTCQATGDP TPTIHWVRKS DGQILTRRGN RSVETCESNV
RDQQASDTRA AKTWADAGQA LQERGRRREG KRSLQTGGQK LGLDPFPGLS LCLGLTAVSL
CRCVQRPGDR MDIREDTRST TFTLRQIVPS DGGMYTCIAS NTVGKASQDL SLQTPPAAPQ
QVRAHASPTS VRLSLDAPLA DGGSPLLQLR LQWREVAASE WRQELVGAGG RCSAQSRDAL
VITGLQPYTS YSVQLSAING VGEGNMSQEQ TVRTVGIREP DKPVISKEGT SEGNTYRIPF
KQLDDGGKPI IKYIVRYRSE DSQLEKEMEL PADSKEVILK DLDYNTEYGV EILAVNSNGT
SAPANISFLI PQPISTKDAR SSPQKSGMGT GGIVGIVMVI FLVVLIAADA TCFYTNRCGM
LMCIAVNLLG RRPRGTKGLD PEE
//
