ID W5M920_LEPOC Unreviewed; 560 AA.
AC W5M920;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=TBCC domain-containing protein 1 {ECO:0000256|ARBA:ARBA00017559};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000004879.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000004879.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm,
CC cytoskeleton, spindle pole {ECO:0000256|ARBA:ARBA00004647}.
CC -!- SIMILARITY: Belongs to the TBCC family.
CC {ECO:0000256|ARBA:ARBA00008848}.
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DR EMBL; AHAT01011430; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006636353.1; XM_006636290.2.
DR AlphaFoldDB; W5M920; -.
DR STRING; 7918.ENSLOCP00000004879; -.
DR Ensembl; ENSLOCT00000004887.1; ENSLOCP00000004879.1; ENSLOCG00000004084.1.
DR GeneID; 102696658; -.
DR KEGG; loc:102696658; -.
DR CTD; 55171; -.
DR eggNOG; KOG4416; Eukaryota.
DR GeneTree; ENSGT00470000042284; -.
DR HOGENOM; CLU_016712_1_1_1; -.
DR InParanoid; W5M920; -.
DR OMA; FYEWLVQ; -.
DR OrthoDB; 3019544at2759; -.
DR Proteomes; UP000018468; Linkage group LG12.
DR Bgee; ENSLOCG00000004084; Expressed in ovary and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0031616; C:spindle pole centrosome; IBA:GO_Central.
DR GO; GO:0051661; P:maintenance of centrosome location; IBA:GO_Central.
DR GO; GO:0051684; P:maintenance of Golgi location; IBA:GO_Central.
DR Gene3D; 2.160.20.70; -; 1.
DR InterPro; IPR017901; C-CAP_CF_C-like.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR036223; CAP_C_sf.
DR InterPro; IPR006599; CARP_motif.
DR InterPro; IPR039589; TBCC1.
DR InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR PANTHER; PTHR16052:SF0; TBCC DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16052; UNCHARACTERIZED; 1.
DR Pfam; PF07986; TBCC; 1.
DR SMART; SM00673; CARP; 1.
DR SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468}.
FT DOMAIN 306..437
FT /note="C-CAP/cofactor C-like"
FT /evidence="ECO:0000259|PROSITE:PS51329"
FT REGION 142..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 62479 MW; B1E7E57F4043F002 CRC64;
MEQRSVSVWP RLEPFLLGVL PAAPPAKFSM HYLRKMAAYV RARTREGCFP RLHWPLWRHI
ACGKLQLPED TAWLYFETCD LLAPRPSEER LEWAEAVSQC GSVEELDKLR YKLSVDTLQF
LLFLYIQQLN RVSLRTSLIG EEWPSPRSRS RSPSPDRDAK TAAQNKNWDD QAHLSFIQTH
LSDLLELVLE PEQLGGPGQA VHDSQVSAEA LRGLSFLLEG SLSRGRAVHG LHELLGWGPL
QAQAGYSALT HSFSLPRLQA WLRESLTANP FGTTACLRSG KKLAWAQQVD GAMKRAKIAR
NTHIAPPGSR VVLMSQVYRQ TVAKDSEKLA GANVKLHRCS EAYIYLLTPL RSVSVEKCRN
TTVVLGPVQS TVHVQSCEDV CVVCVAGRLS VGASSRCTFH ALTPTRPLLL PGNEALTLAP
FHTHYPSLED HMASVGLAVV PSSWDQPLLL GSEGPLGNPP YRLLPPSEFC PLVVPFEMEG
DTTEIPGGLP PQYQKALTAR EQRVQNWQRT VKEAKLNKEQ RRQFQALVEQ KFHEWLLESG
HRQQLDSLIP APPETKQAAG
//
