ID W5MAI1_LEPOC Unreviewed; 384 AA.
AC W5MAI1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=PLAT domain-containing protein {ECO:0000259|PROSITE:PS50095};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000005390.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000005390.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; AHAT01010521; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5MAI1; -.
DR Ensembl; ENSLOCT00000005398.1; ENSLOCP00000005390.1; ENSLOCG00000004480.1.
DR GeneTree; ENSGT00940000168098; -.
DR HOGENOM; CLU_009624_2_0_1; -.
DR Proteomes; UP000018468; Linkage group LG23.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0001822; P:kidney development; IEA:InterPro.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR000434; PC1.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR10877:SF136; POLYCYSTIC KIDNEY DISEASE PROTEIN 1-LIKE 3; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF01477; PLAT; 1.
DR PRINTS; PR00500; POLYCYSTIN1.
DR SMART; SM00308; LH2; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR PROSITE; PS50095; PLAT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 109..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 153..270
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
SQ SEQUENCE 384 AA; 43582 MW; D3D7EB6450B84E22 CRC64;
GYRWLLTPEL LSVGSGNWHV LITPFNLSNG ESVTLRVLIF TSEIFLHWLD ENDPGSPKSY
FVHSNTEPWL TECLCNHLTF FGSSFFVLPN QVDLSRTAEY FATVTKNPVV VILLSVFFGL
YLITVIWAWN ADKKALKKRK LTVLDDNHPC AQYYYMLKVE TGHRSGAGTS AKVQATLLGS
EDQSEPHHLN DPDKPVFERG GVDLFLLSTA FSLGELQNIR LWHDNTGGHP SWYVDKVVVQ
DVQTRQCWHF LCSTWLSSSK GDRMTDRTFN PAKKNEITSF SNIFQSKATI GFRDEHIWIS
ILDPPKRSPF TRVQRVSCCM CLLLCTMAIN IIFFNLPADS SSPVLISIGS VKITWQEIMI
GIESGLLMFP INILIITIFR NIRP
//
