ID W5MCA5_LEPOC Unreviewed; 374 AA.
AC W5MCA5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Rab9 effector protein with kelch motifs {ECO:0000256|ARBA:ARBA00039295};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000006014.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000006014.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Rab9 effector required for endosome to trans-Golgi network
CC (TGN) transport. {ECO:0000256|ARBA:ARBA00037224}.
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DR EMBL; AHAT01024972; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015222615.1; XM_015367129.1.
DR AlphaFoldDB; W5MCA5; -.
DR STRING; 7918.ENSLOCP00000006014; -.
DR Ensembl; ENSLOCT00000006022.1; ENSLOCP00000006014.1; ENSLOCG00000004994.1.
DR GeneID; 102688409; -.
DR CTD; 10244; -.
DR eggNOG; KOG0379; Eukaryota.
DR GeneTree; ENSGT00940000158763; -.
DR HOGENOM; CLU_045313_0_0_1; -.
DR InParanoid; W5MCA5; -.
DR OMA; CTPGSIW; -.
DR OrthoDB; 5474681at2759; -.
DR Proteomes; UP000018468; Linkage group LG21.
DR Bgee; ENSLOCG00000004994; Expressed in testis and 13 other cell types or tissues.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR46647; RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS; 1.
DR PANTHER; PTHR46647:SF1; RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR Pfam; PF13415; Kelch_3; 1.
DR Pfam; PF13418; Kelch_4; 2.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 313..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 40296 MW; 73E96ACE7FFE88DA CRC64;
MELLQVLEPE DKPQESTWYA LVPAGEGPGE RVGHTCTYIP GKDGHKGKIL IVGGANPNGS
FSDSYIIDLG AHEWDMPDWE GLLPRYEHCS FVPQSRPGSL WVFGGAEQNG NRSCVQELQM
EAGSWRSVKV CGTPPSARTY HTCSACIGDR LYVFSGGDQG AAPVSDSQLH VFDSASLTWS
QPQTQGKPPS PRHGHVIVSV GSKLYIHGGL AGEALHSDLH CIDTTDMRWE RVRTKGDVPP
GCAAHSAAAL GKVIYIFGGM TAAGAVNSMY KFHIDRQRWT LVTFGGALPS KRLDHSMCVV
PWRLRASGDV SRALADTGGG GDKDDPAESL PRRQQEENSS LSSPGEFVHL CFVFGGMDTE
GNIYNDCAVA VLSQ
//
