ID W5MEX7_LEPOC Unreviewed; 1662 AA.
AC W5MEX7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Zonadhesin {ECO:0008006|Google:ProtNLM};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000006936.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000006936.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AHAT01015208; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01015209; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7918.ENSLOCP00000006936; -.
DR Ensembl; ENSLOCT00000006944.1; ENSLOCP00000006936.1; ENSLOCG00000005742.1.
DR eggNOG; KOG1216; Eukaryota.
DR GeneTree; ENSGT00940000156850; -.
DR HOGENOM; CLU_001167_0_0_1; -.
DR InParanoid; W5MEX7; -.
DR OMA; PACNETD; -.
DR Proteomes; UP000018468; Linkage group LG14.
DR Bgee; ENSLOCG00000005742; Expressed in mesonephros and 1 other cell type or tissue.
DR GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd19941; TIL; 4.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000998; MAM_dom.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR025615; TILa_dom.
DR InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR InterPro; IPR001007; VWF_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR46160; ALPHA-TECTORIN-RELATED; 1.
DR PANTHER; PTHR46160:SF4; VWFD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08742; C8; 4.
DR Pfam; PF01826; TIL; 4.
DR Pfam; PF12714; TILa; 4.
DR Pfam; PF00094; VWD; 4.
DR SMART; SM00832; C8; 4.
DR SMART; SM00214; VWC; 4.
DR SMART; SM00215; VWC_out; 3.
DR SMART; SM00216; VWD; 4.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57567; Serine protease inhibitors; 4.
DR PROSITE; PS50060; MAM_2; 1.
DR PROSITE; PS51233; VWFD; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 118..289
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 495..669
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 818..867
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 887..1066
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1277..1449
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
SQ SEQUENCE 1662 AA; 185138 MW; 29193E63AEFCEF36 CRC64;
PVCTPNSHYD SCASACPATC ALPNAPFSCE WPCVEGCVCN IGYLLNEGRC VPSNQCGCWD
NGVYYSPGSG FWTDDTCSTQ CTCPSLGGHL TCSSASCPSD HYCGISSGVP DCYPSTFGIC
KLHNGPHYNT FENTLHQFMG TCTYTLAKLC MKSSSIPYFS VKVKIENRGN FSNFYIHELH
VNVYNYIISM FKELRDKVNG LWRKLPVSLS GESVRIHKRG RLIVLKTGFD LKLSYNADYM
VEVKVPSLYF NKTCGMCGNY NHFRQNLLVK DKTEIQSSWQ DSPGDLTCEP TVPPHPCPHS
KEQNYKGDQM CGLITSTNGY FSQCLSVVNP ESFFQQCVFH MCAQNGDLNV LCNILQAYAD
ACQSAGLILP IWRNASFCPL TCTANSHYNS CTSACPETCM DRDAPATCKR PCVEGCECDN
GFLLSGGRCI VPDNCGCWVN GQYYEKEDTF MDGNCESMCR CLGNNNITCS PVSCRQDEVC
KIKDGFLGCF RTSAATCHIF GDPHYSTFDG KLYHLQGSCN YTVVQTCVNS SVHFTVSSRN
EHRVIPGLSA LNSVALEVQG LHIALRKDKN VYINGMLATL PVLESKIHVF YEGSYIHVET
TFGLRLLFDG DHSLFVQIDE RYKGKICGLC GTYSDSQLDD FMTPDGTLVH SPEDFGKSWR
IQDDEWICNS DPPPVLPCNP QLDSEAFQKC SVLFAAPGPF EKCHWFIPPQ LYVDSCVYDH
CATGGDVHQL CTSLESYAAA CEVAKVNLGN WREKTICVLT CPLNCNFDSD TRIGPVNAEM
ICQHAHCPIR SVNFDICIVL FIKSHNLFKN GIVIVCLLDC NFEKDFCGWS QPLTGSLHWT
RHLETTSSTF SGPSFNHTTR VYQYFTGNIC KDQLIVFPII VIVSGASFCH IAGDPHYFTF
DKVMHTFVGA CAYTLVKVCQ TDGSVTPITI SGLNEAHGQP EATYLKQVDI TVYNNKLSIL
KDKQLLLNGK EISNMDQPLA KGITVTSQRL YTTVLTDFGV SVKFDGKQHL EIRLPPEYFS
KVCGMCGNNN NRQDDELLLP DGQLAHNVSH FGNSWKIDED SPPECLADER EDLGSPCKTD
QKPEIEKQCE VLLSETFKPC HSVIPPEHFI ESCVYDMCKY LGMISTLCDM IQAYVSACRS
EGVHINWRRG DFCPLSCPKN SHYTVCVPAC QPTCADLHAS VHCDKVQSCV EGCVCNNGYV
LSEDKCVPIR KCGCQDKKGN YYKVSESWIT DHCSQKCKCE EEDDHAEIDC DDYGCDDDSV
CALSENGEYK CKPTDFSECS VSGDPEYKTF DNMEHQFEGR HSYILVQTVH IPKDLPEIYI
EGINGLKGLT TLKEIKIRVY NHTVKFKHKR KLVLDGEKVK PPTIPHRGMK ITQRSSLLFL
ETDFGLSVKF DGHDHAEITL PYTYQNKIVG LCGNYDGDKN NDFMKPDGSQ AKNMNEFGES
WQVQTSHSDA AIQDYNNTGV SATISFQCTE QQKTLLNSMR FCGIISDPQG PFSTCHGAVQ
PVKHLENCVA DQCSSFNNTS LLCKSLQRYS EACQKRGISI GNWRASTLCE MKCPSHSEYR
LCMTACPPSC GNLANPRDCE APCQEGCQCL PGFVHSNFDC VPYKECGCFY HNVYHKDGET
FVTEDCAQNC TCSDTSVTCR PMKCPSGLVC RTSNMIRGCY EA
//
