ID W5MJE6_LEPOC Unreviewed; 2427 AA.
AC W5MJE6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Chondroitin sulfate proteoglycan 4-like {ECO:0000313|Ensembl:ENSLOCP00000008505.1};
OS Lepisosteus oculatus (Spotted gar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Holostei; Semionotiformes; Lepisosteidae;
OC Lepisosteus.
OX NCBI_TaxID=7918 {ECO:0000313|Ensembl:ENSLOCP00000008505.1, ECO:0000313|Proteomes:UP000018468};
RN [1] {ECO:0000313|Proteomes:UP000018468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E.S., Lindblad-Toh K.;
RT "The Draft Genome of Lepisosteus oculatus.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLOCP00000008505.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR EMBL; AHAT01014568; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01014569; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AHAT01014570; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 7918.ENSLOCP00000008505; -.
DR Ensembl; ENSLOCT00000008515.1; ENSLOCP00000008505.1; ENSLOCG00000007013.1.
DR eggNOG; KOG3597; Eukaryota.
DR GeneTree; ENSGT00940000154091; -.
DR InParanoid; W5MJE6; -.
DR Proteomes; UP000018468; Linkage group LG2.
DR Bgee; ENSLOCG00000007013; Expressed in heart and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR45739:SF12; CHONDROITIN SULFATE PROTEOGLYCAN 4-LIKE ISOFORM X2; 1.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF16184; Cadherin_3; 13.
DR Pfam; PF02210; Laminin_G_2; 2.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR PROSITE; PS51854; CSPG; 10.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018468};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2302..2325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..227
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 237..416
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REPEAT 460..555
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 585..679
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 928..1022
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1162..1252
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1274..1373
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1389..1482
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1506..1596
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1613..1713
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1738..1837
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1871..1963
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REGION 2336..2356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2427 AA; 272869 MW; B4D182AAD936F8A8 CRC64;
MSVFFVGYRG VSVLYDCRQS VXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
XXXXXKTVES SSRTSFHARF RTSSPNGLLF LAAGQTDYCL VELHSARLQV KLDLGSGERI
LRSERGTPLN DLAWHTVEFQ HENHNVTLSV DKHFQTTLKM PESQHDLNIQ DGLYVGGTGG
LDKSYLLSEP VGFRGCIDEL LFNQHNLLSS LRSYSGFKNV YEVSLGCSPQ FFASEDDPIS
FFSSKAYISL PLWNAQQEGV LECVLHTSAD QGIILYNSAR QGDFVAMEIR DGLIVAVMGK
SGTKSELPSL TYINDRKWHY IKLQFTSRSL QLTVDEETVK TSISSRNKAL QLRGSLFVGG
IDDSTRAEVK KVGLVSVSGK RIRGGSFKGC LKDIKVNFVK MGLPNALVTK DISVGCEPEK
EPEPTTQTTP ATHWAQTAPV LPTTSMFTPT SAKPLDKKRS QMFLVLRNLV VPEGGRAPLE
SKHIKVNLEF KKLGIRQSQI MFKIQEQPVH GQLRLDVDEG QEEHTFSMLD LWHGRVMYIH
GGSEDPEDFF TFSVFTSSKK EVPPYLKGNK MYRYNITITP TNDAPELSLP EGNLFVLLEK
SRKHLTIDAL KATDVDNNST DLFFSLLGNL NADAGFLENT ENPGKSITTF SHVDLEEGKI
NYVHSGVRNS RIVLRVSDGE KVSNTVVLRI MAIPLEYKVA NITGLDVLQG DAALISTKDL
AIQTNAVKQE LEIRYDVTES PKYGELQRLN SNGEWKQTSL FSQRTLERDR LRYLSTFYEI
QSSNVSDHFK CKVSISSMAT EEVVFPIMIK WVQYKLLKNK VMEVDKAQRV ILNSEHLHAI
PKGVKLTENE LYFRLLTLPK KGKLLLNNKI LKKNSTFSQR NITDLKVHYE LQDRPYEDTR
DMFTFQIFSK HAQSGIYDFK IAIKADINSI IIKNNGLSLK EGESQLLTKE ELFSETLITK
SMHYRITDRP KHGKLIRINL SNSTSSNDNI IAFTNQDILE ERIMYVHDDS ETTHDQFTFV
ASTQQPAKES GPVAETNIVE STFNISIKLI NDEKPVRIVD EVFHVVKNGQ RLLTLEDLCY
HDADSDFDDG QLLYTRRGIP MGDLVLVNDT SHKLYQFHQE DLEQKRVLFV HHGPNIGRFV
LFVSDGKHYT STLLDVSAQE PYIKTANNTG LLVQKGQQKM FSSANFSVVT NLDVRDDKEI
IYEMYLPPKH GGLYQDELKV DVFTQHDLKK GYLVYRHDDS KNLVDFFNFT VKVQKMRLDA
GVNIKVYLES HQLPPKVMHN NTLLVEEGKP VKISKRKLEV THEDNLPSEI VYTVKVPPSH
GYIRSFAEGE EHYLGSENNP IWSFSQQDIN DGNIQYVQVE ADQLTDCIVL DVSNGITEVN
GIMILIEIIP RMIPLEIYNI TLKEGASKAL TEDVIKVNNK HFAALSFQYF IWDPPKHGHI
EHSRYPGVHL SSFTRTQVEQ EFVYYVHDDS ETVSDNFTII ANDTELRKKS LPWTVFVNIT
PVNDEPPVVT ANRIFRVWVS SVTEITEEDL NAEDRDSPPE DLEYIVTPPS NGHLALKNSA
NKHIFNFTQA HINQGQLVFV HSGAMSGGFN FQVNDGMNFA QRQIFSITAR ALVLSLEKTK
PLKVFPGSLT VLSTENLQAV TNDNSATGNR TITFTLISTP KLGNLVKIEA DNSTSEMSSF
TQIMVDDGVI AYKQSNVEPV GWSAVDSFRF SVSSPPASLE PHVFNIDISY ENTGPESKSL
LLANTGATVT EGEKVVIDKS KLDASNLMAK LPEDQRNSYE VWFQVVSFPQ HGVIIVGERN
LTKEKPNFSQ FIVNKYGITY LHDNSETTYD SFLFNSWLNL KSKPASRPQD GSNVVEELFN
ITIIPVNDQP PQLKTKSPSL RVVQGDKAVL GPENLNVVDL DNPPEDIKYT IITKPSNGFM
AVEGHLNESI MAFTQADLNS GKVWFVQDGT PFSGVFYFSV TDGQHRPIYK LFNLQVTAIS
VFLLNNTDLV LEQGQNSAIL TNEHLAAETN GKSTAIQYQV TTPPQYGSLL IDNEVVTQFD
QDDLQQKRLS YHMINLMSSK DSFEFTAFTS ESNLTQQVVN ITVKPLIKLR NDVKIPCGVI
VKLRKDMLNA TELSILSGSD PHFEILYPPK HGNIFKALTV KDRPSQPLQS FTFDDLDQGK
IAIKVNVNMT GVEEMNDSFV FVLQADKVQP AVGEFTYTVV PYDPTLLPAV TTEGPLQTTR
TPVNQTTPQE STLHLPLEPV LATQKPVKTV QRWKGRNRWG TQNRNNVSVP SVTKATSGKQ
ETTRKNTAVR VESFPRKASN PLLIILPLLA CLLLIIILVV LILVFRHRRE KQKPLIQNHP
NNNIPPSSPH LGQPERSLTI PSVTVTPLHT DNVGSPLLLG PQGHTVVAPG SPQDTSLLLC
SWNNLDPETL QHCRTTNPSL RHNQYWV
//
